Journal Articles

Article Open Access

MUC13 promotes lung cancer development and progression by activating ERK signaling

Yao Pang, Yu Zhang, Hong-Yi Zhang, Wen-Hao Wang, Gang Jin, Jia-Wei Liu, Zi-Jiang Zhu

Article Number: 37 Published online on: 01 December 2021
Article

GPNMB overexpression is associated with extensive bone metastasis and poor prognosis in renal cell carcinoma

Jian-Po Zhai, Zhen-Hua Liu, Hai-Dong Wang, Guang-Lin Huang, Li-Bo Man

Article Number: 36 Published online on: 01 December 2021
Article

Correlation between promoter methylation of the LDH‑C4 gene and DNMT expression in breast cancer and their prognostic significance

Jiandong Zhang, Fengxia Zhang, Fengqin Zhang, Hua Wu, Bei Zhang, Xiangyun Wu

Article Number: 35 Published online on: 01 December 2021
Correction Open Access

[Corrigendum] Dihydroartemisinin suppresses proliferation, migration, the Wnt/β‑catenin pathway and EMT via TNKS in gastric cancer

Yanmei Ma, Peng Zhang, Qilong Zhang, Xiaofei Wang, Qiong Miao, Xiaolan Lyu, Bo Cui, Honghong Ma

Article Number: 34 Published online on: 30 November 2021
Article Open Access

Antitumor effects of cadmium against diethylnitrosamine‑induced liver tumors in mice

Yu Nie, Bo Huang, An-Ling Hu, Yun-Yan Xu, Yan Zou, Yun Liu, Jie Liu

Article Number: 33 Published online on: 26 November 2021
Article Open Access

Inositol 1,4,5‑trisphosphate receptor type 3 is involved in resistance to apoptosis and maintenance of human hepatocellular carcinoma

Marcone Loiola Dos Santos, Andressa França, Antônio Carlos Melo Lima Filho, Rodrigo M. Florentino, Paulo Henrique Diniz, Fernanda Oliveira Lemos, Carlos Alberto Xavier Gonçalves, Vitor Lima Coelho, Cristiano Xavier Lima, Giselle Foureaux, Michael H. Nathanson, Paula Vieira Teixeira Vidigal, M. Fátima Leite

Article Number: 32 Published online on: 25 November 2021
Article Open Access

Potential anticancer effect of aspirin and 2'‑hydroxy‑2,3,5'‑trimethoxychalcone‑linked polymeric micelles against cervical cancer through apoptosis

Kang Pa Lee, Suji Baek, Myeong Sik Yoon, Ji Soo Park, Bok Sil Hong, Sang Ju Lee, Seung Jun Oh, Seung Hae Kwon, Ruda Lee, Dae Ho Lee, Kang-Seo Park, Byung Seok Moon

Article Number: 31 Published online on: 25 November 2021
Article Open Access

Evaluation of dyskerin expression and the Cajal body protein WRAP53β as potential prognostic markers for patients with primary vaginal carcinoma

Cecilia Ranhem, Gabriella Lillsunde Larsson, David Lindqvist, Bengt Sorbe, Mats G. Karlsson, Marianne Farnebo, Kristina Hellman, Larysa Kovaleska, Elena Kashuba, Sonia Andersson

Article Number: 30 Published online on: 23 November 2021
Article Open Access

Expression of non‑homologous end joining factor, Ku80, is negatively correlated with PD‑L1 expression in cancer cells after X‑ray irradiation

Takuya Kumazawa, Yasumasa Mori, Hiro Sato, Tiara Bunga Mayang Permata, Yuki Uchihara, Shin-Ei Noda, Kohei Okada, Sangeeta Kakoti, Keiji Suzuki, Hayato Ikota, Hideaki Yokoo, Soehartati Gondhowiardjo, Takashi Nakano, Tatsuya Ohno, Atsushi Shibata

Article Number: 29 Published online on: 23 November 2021
Article

Zinc‑finger protein 750 mitigates malignant biological behavior of oral CSC‑like cells enriched from parental CAL‑27 cells

Cong Xu, Hong-Li Yang, Yi-Kun Yang, Li Pan, Hai-Ying Chen

Article Number: 28 Published online on: 19 November 2021
Article Open Access

RBM38 is negatively regulated by miR‑320b and enhances Adriamycin resistance in breast cancer cells

Jing Ke, Kan Ni, Huimin Xue, Jia Li

Article Number: 27 Published online on: 19 November 2021
Review Open Access

MCP‑1 targeting: Shutting off an engine for tumor development (Review)

Liang Wang, Jinxin Lan, Jiaping Tang, Na Luo

Article Number: 26 Published online on: 19 November 2021
Article

Baseline lymphopenia as prognostic factor in patients with metastatic breast cancer treated with palbociclib

George Emile, Sarah Penager, Christelle Levy, Alison Johnson, Djelila Allouache, Justine Lequesne, Ioana Hrab, Carine Segura, Adeline Morel, Katarina Gunzer, Audrey Faveyrial, Francois Cherifi, Angelique Da Silva

Article Number: 25 Published online on: 19 November 2021
Article Open Access

Long non‑coding RNA MIR17HG sponges microRNA‑21 to upregulate PTEN and regulate homoharringtonine‑based chemoresistance of acute myeloid leukemia cells

Jinhua Yan, Ling Yao, Ping Li, Guohe Wu, Xiaobin Lv

Article Number: 24 Published online on: 18 November 2021
Article

mRNA expression of specific HER ligands and their association with clinical outcome in patients with metastatic breast cancer treated with trastuzumab

Vassiliki Rapti, Evangelia Moirogiorgou, Georgia-Angeliki Koliou, Kyriaki Papadopoulou, Ioannis Binas, George Pentheroudakis, Dimitrios Bafaloukos, Mattheos Bobos, Kyriakos Chatzopoulos, Sofia Chrisafi, Christos Christodoulou, Irene Nicolaou, Maria Sotiropoulou, Christina Magkou, Angelos Koutras, Pavlos Papakostas, Athanasios Kotsakis, Evangelia Razis, Amanda Psyrri, Dimitrios Tryfonopoulos, Dimitrios Pectasides, Eleni Res, Athanasios Alexopoulos, Vassiliki Kotoula, George Fountzilas

Article Number: 23 Published online on: 17 November 2021
Article Open Access

Direct molecular evidence for both multicentric and monoclonal carcinogenesis followed by transdifferentiation from hepatocellular carcinoma to cholangiocarcinoma in a case of metachronous liver cancer

Sumie Ohni, Hiromi Yamaguchi, Yukari Hirotani, Yoko Nakanishi, Yutaka Midorikawa, Masahiko Sugitani, Hiromu Naruse, Tomohiro Nakayama, Makoto Makishima, Mariko Esumi

Article Number: 22 Published online on: 17 November 2021
Review Open Access

Biological function and molecular mechanism of SRSF3 in cancer and beyond (Review)

Jian Xiong, Yinshuang Chen, Weipeng Wang, Jing Sun

Article Number: 21 Published online on: 16 November 2021
Article Open Access

Cordycepin inhibits the proliferation and progression of NPC by targeting the MAPK/ERK and β‑catenin pathways

Yaqi Zhou, Xueshuang Mei, Ying Li, Weiqiang Yang, Xi Su, Hongyi Hu

Article Number: 20 Published online on: 16 November 2021
Article Open Access

Use of oral glutamine in radiation‑induced adverse effects in patients with thoracic and upper aerodigestive malignancies: Results of a prospective observational study

Amalia Papanikolopoulou, Nikolaos Syrigos, Louisa Vini, Maria Papasavva, Georgios Lazopoulos, Stelios Kteniadakis, Demetrios A. Spandidos, Adrianni Charpidou, Nikolaos Drakoulis

Article Number: 19 Published online on: 16 November 2021
Article Open Access

Circulating miRNA expression over the course of colorectal cancer treatment

Eva Kudelova, Veronika Holubekova, Marian Grendar, Zuzana Kolkova, Marek Samec, Barbora Vanova, Peter Mikolajcik, Marek  Smolar, Erik Kudela, Ludovit Laca, Zora Lasabova

Article Number: 18 Published online on: 15 November 2021
Article Open Access

Clinical significance and effect of lncRNA BBOX1‑AS1 on the proliferation and migration of lung squamous cell carcinoma

Yu Zhang, Xiao Wang, Xian-Kui Cheng, Yuan-Yuan Zong, Rong-Quan He, Gang Chen, Ye-Jun Qin

Article Number: 17 Published online on: 12 November 2021
Article Open Access

Luteolin potentiates low‑dose oxaliplatin‑induced inhibitory effects on cell proliferation in gastric cancer by inducing G2/M cell cycle arrest and apoptosis

Jun Ma, Xiaojie Chen, Xuejie Zhu, Zhaohai Pan, Wenjin Hao, Defang Li, Qiusheng Zheng, Xuexi Tang

Article Number: 16 Published online on: 12 November 2021
Article Open Access

MicroRNA‑337‑3p impedes breast cancer progression by targeting cyclin‑dependent kinase 1

Shuxin Kong, Jianyang Liu, Bin Zhang, Feng Lv, Yang Yu, Tao Qin

Article Number: 15 Published online on: 12 November 2021
Article Open Access

Interleukin‑32 regulates downstream molecules and promotes the invasion of pancreatic cancer cells

Kohji Takagi, Akiko Shimomura, Johji Imura, Hisashi Mori, Akira Noguchi, Shinichi Tanaka, Takashi Minamisaka, Takeshi Nishida, Hideki Hatta, Takahiko Nakajima

Article Number: 14 Published online on: 11 November 2021
Article Open Access

Local drug delivery system for the treatment of tongue squamous cell carcinoma in rats

Mariam Z. Kakabadze, Teona Paresishvili, Konstantine Mardaleishvili, Zurab Vadachkoria, Nicholas Kipshidze, Mikheil Jangavadze, Lia Karalashvili, Ketevan Ghambashidze, David Chakhunashvili, Zurab Kakabadze

Article Number: 13 Published online on: 11 November 2021
Article Open Access

Diagnostic and prognostic value of serum miR‑145 and vascular endothelial growth factor in non‑small cell lung cancer

Sarayut Lucien Geater, Pichitpon Chaniad, Keson Trakunram, Warangkana Keeratichananont, Suhaimee Buya, Paramee Thongsuksai, Pritsana Raungrut

Article Number: 12 Published online on: 11 November 2021
Article Open Access

DNMT3B regulates proliferation of A549 cells through the microRNA‑152‑3p/NCAM1 pathway

Bo Yang, Shiqing Huang, Hongming Chen, Rizhu Li, Shihao Hou, Jingjing Zhao, Yepeng Li

Article Number: 11 Published online on: 10 November 2021
Article Open Access

Aberrant expression of SPAG6 may affect the disease phenotype and serve as a tumor biomarker in BCR/ABL1‑negative myeloproliferative neoplasms

Li Ding, Jie Luo, Jing Ping Zhang, Ji Wang, Zhao Quan Li, Juan Huang, Li Chai, Jiao Mu, Beibei Zhao, Yi Rui Zhong, Lin Yi Zhang, Lin Liu

Article Number: 10 Published online on: 10 November 2021
Article Open Access

Role of Lamin A and emerin in maintaining nuclear morphology in different subtypes of ovarian epithelial cancer

Shiori Watabe, Sayaka Kobayashi, Mizuho Hatori, Yoshimi Nishijima, Naoki Inoue, Hayato Ikota, Akira Iwase, Hideaki Yokoo, Masanao Saio

Article Number: 9 Published online on: 09 November 2021
Article Open Access

Isoliensinine induces cervical cancer cell cycle arrest and apoptosis by inhibiting the AKT/GSK3α pathway

Hong-Li Li, Yan Cheng, Zi-Wei Zhou, Hui-Zhi Long, Hong-Yu Luo, Dan-Dan Wen, Lin Cheng, Li-Chen Gao

Article Number: 8 Published online on: 09 November 2021
Article Open Access

Tanshinone IIA potentiates the efficacy of imatinib by regulating the AKT‑MDM2‑P53 signaling pathway in Philadelphia chromosome‑positive acute lymphoblastic leukemia

Yong Guo, Fang-Fang Wang, Bing Xiang, Hong-Bing Ma, Yu-Ping Gong

Article Number: 7 Published online on: 08 November 2021
Article Open Access

Establishment and characterization of prostate organoids from treatment‑naïve patients with prostate cancer

Katia Cheaito, Hisham F. Bahmad, Ola Hadadeh, Hiba Msheik, Alissar Monzer, Farah Ballout, Christelle Dagher, Talar Telvizian, Nour Saheb, Ayman Tawil, Marwan El‑Sabban, Albert El‑Hajj, Deborah Mukherji, Mohamed Al‑Sayegh, Wassim Abou‑Kheir

Article Number: 6 Published online on: 05 November 2021
Review Open Access

SOCS proteins and their roles in the development of glioblastoma (Review)

Lirui Dai, Zian Li, Wulong Liang, Weihua Hu, Shaolong Zhou, Zhuo Yang, Yiran Tao, Xuelei Hou, Zhe Xing, Jianchao Mao, Zimin Shi, Xinjun Wang

Article Number: 5 Published online on: 05 November 2021
Article Open Access

Low prevalence of biliary tract cancer with defective mismatch repair genes in a Japanese hospital‑based population

Yasuhisa Ando, Kensuke Kumamoto, Hiroyuki Matsukawa, Ryou Ishikawa, Hironobu Suto, Minoru Oshima, Hideki Kamada, Asahiro Morishita, Hideki Kobara, Toru Matsunaga, Reiji Haba, Tsutomu Masaki, Yasuyuki Suzuki, Keiichi Okano

Article Number: 4 Published online on: 04 November 2021
Article Open Access

Cancer‑associated fibroblasts as cellular vehicles in endometrial cancer cell migration

Yap Chee Voon, Intan Sofia Omar, Ming-Heng Wu, Nur Akmarina B.M. Said, Ivy Chung

Article Number: 3 Published online on: 04 November 2021
Article Open Access

Block‑Removed Immunoglobulin Technology to enhance rituximab effector function by counteracting CA125‑mediated immunosuppression

Luigi Grasso, James Bradford Kline, Nicholas C. Nicolaides

Article Number: 2 Published online on: 02 November 2021
Review Open Access

Advances in the application of Let‑7 microRNAs in the diagnosis, treatment and prognosis of leukemia (Review)

Hao Chen, Jiewei Wang, Huan Wang, Jingru Liang, Jinhua Dong, Houqiao Bai, Guosheng Jiang

Article Number: 1 Published online on: 02 November 2021
Journal Cover

January-2022
Volume 23 Issue 1

Print ISSN: 1792-1074
Online ISSN: 1792-1082

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