Journal Articles

Open Access

Expression of ubiquitin‑conjugating enzyme E2T in colorectal cancers and clinical implications

Xiangtian Wu, Gang Liu, Ruiting Liu, Jing He, Guorong Wang, Haibao Zhang, Tianjie Liu, Jirong Bai, Ning Cheng, Jian Qiu

Article Number: 275 Published online on: 21 September 2020
Open Access

Water‑soluble propolis and bee pollen of Trigona spp. from South Sulawesi Indonesia induce apoptosis in the human breast cancer MCF‑7 cell line

Eri Amalia, Ajeng Diantini, Anas Subarnas

Article Number: 274 Published online on: 21 September 2020
Open Access

Biomarker heterogeneity between primary breast cancer and synchronous axillary lymph node metastases

Xun Xi, Xing-Wei Huang, Huo-Zhong Yuan, Chun He, Jun Ni, Fu-Lan Yang

Article Number: 273 Published online on: 21 September 2020
Open Access

Impact of inflammation and immunotherapy in renal cell carcinoma (Review)

Jian Shi, Keshan Wang, Zhiyong Xiong, Changfei Yuan, Cheng Wang, Qi Cao, Huang Yu, Xiangui Meng, Kairu Xie, Zhixian Cheng, Hongmei Yang, Ke Chen, Xiaoping Zhang

Article Number: 272 Published online on: 21 September 2020
Open Access

Analysis of vascular‑associated factors and the prognosis of poorly differentiated hypopharyngeal carcinoma

Wei Guo, Gaofei Yin, Hongfei Liu, Hanyuan Duan, Zhigang Huang

Article Number: 271 Published online on: 21 September 2020
Open Access

Agaricus blazei extract (FA‑2‑b‑β) induces apoptosis in chronic myeloid leukemia cells

Yanqing Sun, Mingxia Cheng, Li Dong, Kehu Yang, Zhiyuan Ma, Shangrui Yu, Peijing Yan, Kuntian Bai, Xiaolong Zhu, Qike Zhang

Article Number: 270 Published online on: 21 September 2020

Novel technical modifications of hand‑assisted laparoscopic dissection of a large obturator mass: A case report and literature review

Jun Zhang, Peng Zhong, Haipeng Tong, Jun Jiang, Dali Tong

Article Number: 269 Published online on: 21 September 2020

Role of Wnt5a in suppressing invasiveness of hepatocellular carcinoma via epithelial‑mesenchymal transition

Kazuki Wakizaka, Toshiya Kamiyama, Kenji Wakayama, Tatsuya Orimo, Shingo Shimada, Akihisa Nagatsu, Hirofumi Kamachi, Hideki Yokoo, Moto Fukai, Nozomi Kobayashi, Tomoko Mitsuhashi, Akinobu Taketomi

Article Number: 268 Published online on: 21 September 2020
Open Access

Radiographical efficacy of systemic treatment for bone metastasis from renal cell carcinoma

Takahito Negishi, Nobuki Furubayashi, Dai Takamatsu, Kousuke Ieiri, Naotaka Nishiyama, Hiroshi Kitamura, Motonobu Nakamura

Article Number: 267 Published online on: 21 September 2020

Esophageal squamous cell cancer coincides with myelodysplastic syndrome/acute myelogenous leukemia: A case report and review of the literature

Lingling Liu, Xiaoyun Liu, Yanling Sun, Yinzhu Zeng, Xiaoyun Tang, Xiaoxia Li, Jiajun Liu, Ruozhi Xiao

Article Number: 266 Published online on: 21 September 2020
Open Access

Diabetes and PKM2 affect prognosis in patients with intrahepatic cholangiocarcinoma

Kui Fu, Xiaoli Yang, Hao Wu, Jianping Gong, Xiuyun Li

Article Number: 265 Published online on: 21 September 2020
Open Access

miR‑138‑5p suppresses glioblastoma cell viability and leads to cell cycle arrest by targeting cyclin D3

Henggang Wu, Cheng Wang, Yajun Liu, Chao Yang, Xiaolong Liang, Xin Zhang, Xu Li

Article Number: 264 Published online on: 21 September 2020
Open Access

Circulating miR‑451a levels as a potential biomarker to predict the prognosis of patients with multiple myeloma

Ling Zhong, Xin Jin, Zhuyu Xu, Minghui Zeng, Dongmei Chen, Yuan He, Jianbo Zhang, Tao Jiang, Jiao Chen

Article Number: 263 Published online on: 21 September 2020
Open Access

LINC00294 induced by GRP78 promotes cervical cancer development by promoting cell cycle transition

Jiangnan Qiu, Shulin Zhou, Wenjun Cheng, Chengyan Luo

Article Number: 262 Published online on: 21 September 2020
Open Access

Steroid 5 alpha-reductase 2 enzyme variants, biomass exposure and tobacco use in Mexican patients with prostate cancer

Jesus Rolando Delgado‑Balderas, Hugo Leonid Gallardo‑Blanco, Juan  Felipe Yee‑De León, Ana Maria Rivas‑Estilla, Brenda  Soto‑García, Diana Aráiz‑Hernández, Raquel Garza‑Guajardo, Melissa  Náñez‑Marín, David Hernández‑Barajas, Aldo Missael García‑Bailón, Guillermo  Vízcarra‑Mata, Marco Alberto Ocaña‑Munguía, Lauro   Salvador Gómez‑Guerra, Celia Nohemí Sánchez‑Domínguez

Article Number: 261 Published online on: 18 September 2020

miR‑4295 promotes cell proliferation, migration and invasion of osteosarcoma through targeting interferon regulatory factor 1

Jin Pei Cheng, Bin Huang, Jun Hu Duan, Kai Jun Yi, Zheng Ling Zhuang

Article Number: 260 Published online on: 18 September 2020
Open Access

Prognostic value of immune related genes in lung adenocarcinoma

Han Wang, Meng-Sen Wang, Ying Wang, Yue-Qing Huang, Jian-Ping Shi, Zhi-Liang Ding, Wen-Jie Wang

Article Number: 259 Published online on: 18 September 2020
Open Access

CXCL5 expression in tumor tissues is associated with poor prognosis in patients with pancreatic cancer

Bin Wu, Jing Wang, Xiaoguang Wang, Mingyuan Zhu, Fei Chen, Yiyu Shen, Zhengxiang Zhong

Article Number: 257 Published online on: 18 September 2020
Open Access

Prognostic value of immune scores in the microenvironment of colorectal cancer

Wenliang Yuan, Wei Cai, Xiao Huang, Sihua Peng

Article Number: 256 Published online on: 18 September 2020
Open Access

Mammaglobin B may be a prognostic biomarker of uterine corpus endometrial cancer

Jie Li, Wenwen Xu, Yuxi Zhu

Article Number: 255 Published online on: 18 September 2020
Open Access

Diagnostic value and clinical significance of circulating miR‑650 and CA211 in detecting of gastric carcinoma

Jianlin Chen, Lihua Wu, Yifan Sun, Changjun Luo, Xianhua Chen, Lihong Wu, Junping Ding, Gangxi Pan, Chaowen Han, Zijuan Wu, Yongqi Shen

Article Number: 254 Published online on: 18 September 2020
Open Access

Calcitonin gene‑related peptide: A promising bridge between cancer development and cancer‑associated pain in oral squamous cell carcinoma (Review)

Yu Zhang, Chengzhong Lin, Xu Wang, Tong Ji

Article Number: 253 Published online on: 18 September 2020
Open Access

Two common polymorphic variants of OATP4A1 as potential risk factors for colorectal cancer

Veronika Buxhofer‑Ausch, Orsolya Német, Majdah Sheikh, Hajnalka Andrikovics, Angelika Reiner, Christoph Ausch, Diana Mechtcheriakova, Attila Tordai, Andreas Gleiss, Csilla Özvegy‑laczka, Walter Jäger, Theresia Thalhammer

Article Number: 252 Published online on: 17 September 2020
Open Access

Brother of regulator of imprinted sites inhibits cisplatin‑induced DNA damage in non‑small cell lung cancer

Yanmei Zhang, Yongfei Song, Chao Li, Juan Ren, Mengdie  Fang, Jianfei Fang, Xiaoju Wang

Article Number: 251 Published online on: 17 September 2020
Open Access

TUFM‑knockdown inhibits the migration and proliferation of gastrointestinal stromal tumor cells

Xiaoyuan Weng, Song Zheng, Hanli Shui, Guosheng Lin, Yongjian Zhou

Article Number: 250 Published online on: 17 September 2020
Open Access

Metformin regulation of progesterone receptor isoform‑B expression in human endometrial cancer cells is glucose‑dependent

Sofia Jade U. Saguyod, Iad Alhallak, Rosalia C.Μ. Simmen, Michael C. Velarde

Article Number: 249 Published online on: 17 September 2020
Open Access

Optimized algorithm in solid thyroid nodule elastography

Hao Wu, Qin Chen, Yingxian Liu, Jidong Chen, Wanyue Deng

Article Number: 248 Published online on: 16 September 2020
Open Access

Gemcitabine resistance in triple‑negative breast cancer cells can be reverted by Drosophila melanogaster deoxyribonucleoside kinase in the nucleus or cytosol

Yan Zhao, Haiyang Jiang, Ming Gu, Cong Zu, Xinyu Zheng

Article Number: 247 Published online on: 15 September 2020

USP22 promotes proliferation in renal cell carcinoma by stabilizing survivin

Ying Lin, Hongbin Zhong, Baicheng Sun, Yongtiao Peng, Fuhua Lu, Miaoxuan Chen, Maoshu Zhu, Jiyi Huang

Article Number: 246 Published online on: 15 September 2020

RAB31 is targeted by miR-26b and serves a role in the promotion of osteosarcoma

Qing Wu, Qiong Feng, Yanfei Xiong, Xing Liu

Article Number: 244 Published online on: 15 September 2020
Open Access

[Corrigendum] Anthelmintic pyrvinium pamoate blocks Wnt/β-catenin and induces apoptosis in multiple myeloma cells

Fang Xu, Yingjie Zhu, Yuhong Lu, Zhi Yu, Jun Zhong, Yangqiu Li, Jingxuan Pan

Article Number: 243 Published online on: 15 September 2020

Patterns of recurrence in patients with curative resected rectal cancer according to different chemoradiotherapy strategies: Does preoperative chemoradiotherapy lower the risk of peritoneal recurrence?

Hyungwoo Cho, Jeong Eun Kim, Sun Young Kim, Kyu-Pyo Kim, Tae Won Kim, Jin-Hong Park, Jong Hoon Kim, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim, Yong Sang Hong

Article Number: 242 Published online on: 15 September 2020
Open Access

KIF9‑AS1 promotes nasopharyngeal carcinoma progression by suppressing miR‑16

Huizeng You, Shuyong Wang, Sa Yu

Article Number: 241 Published online on: 15 September 2020
Open Access

ANGPTL1 is a potential biomarker for differentiated thyroid cancer diagnosis and recurrence

Rongxin Sun, Longyan Yang, Yangping Hu, Yan Wang, Qiang  Zhang, Yuanyuan Zhang, Zhili Ji, Dong Zhao

Article Number: 240 Published online on: 15 September 2020
Open Access

[Retracted] Mitochondria targeting nano agents in cancer therapeutics (Review)

Xiao-Ying Zhang, Pei-Ying Zhang

Article Number: 238 Published online on: 14 September 2020
Open Access

[Retracted] Nanotechnology for multimodality treatment of cancer (Review)

Xiao-Ying Zhang, Pei-Ying Zhang

Article Number: 237 Published online on: 14 September 2020
Open Access

A three serum miRNA panel as diagnostic biomarkers of radiotherapy‑related metastasis in non‑small cell lung cancer

Jin Lv, Juan An, Yang-Dong Zhang, Zhao-Xia Li, Guang-Li Zhao, Jun Gao, Wen-Wei Hu, Huo-Ming Chen, Ai-Min Li, Qi-Sheng Jiang

Article Number: 236 Published online on: 14 September 2020
Open Access

miR‑181a‑5p inhibits the proliferation and invasion of drug‑resistant glioblastoma cells by targeting F‑box protein 11 expression

Xueyan Wen, Songrong Li, Mengchan Guo, Hongzhan Liao, Yongmin Chen, Xi Kuang, Xiaoping Liao, Lin Ma, Qifu Li

Article Number: 235 Published online on: 14 September 2020
Open Access

Targeting tumor‑associated macrophages in the tumor microenvironment (Review)

Kaiwen Zhou, Tan Cheng, Jinyue Zhan, Xuan Peng, Yue  Zhang, Jianpei Wen, Xiaoman Chen, Muying Ying

Article Number: 234 Published online on: 14 September 2020
Open Access

The modulation relationship of genomic pattern of intratumor heterogeneity and immunity microenvironment heterogeneity in hepatocellular carcinoma

Liu-Bo Li, Lu Yang, Guo-Qun Xie, Xiao-Cui Zhou, Xu-Bo Shen, Qiu-Lin Xu, Zheng-Yuan Ma, Xiao-Dong Guo

Article Number: 233 Published online on: 11 September 2020
Open Access

High expression of TOP2A in hepatocellular carcinoma is associated with disease progression and poor prognosis

Hongyu Cai, Bingfeng Shao, Yuan Zhou, Zhong Chen

Article Number: 232 Published online on: 11 September 2020
Open Access

Establishment and characterization of a docetaxel‑resistant human prostate cancer cell line

Jian Liu, Yujie Huang, Danyan Zhu, Yao Dai, Dan Liu, You Zhai, Xingguang Liang, Lihua Wu, Qingwei Zhao

Article Number: 230 Published online on: 11 September 2020

Interaction of head and neck squamous cell carcinoma cells and mesenchymal stem cells under hypoxia and normoxia

Christian Wilhelm, Agmal Scherzad, Maximilian Bregenzer, Till Meyer, Thomas Gehrke, Norbert Kleinsasser, Rudolf Hagen, Stephan Hackenberg

Article Number: 229 Published online on: 11 September 2020
Open Access

Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang  Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen

Article Number: 228 Published online on: 11 September 2020
Open Access

BCLAF1 induces cisplatin resistance in lung cancer cells

Tao Jiang, Bingjie Liu, Dongping Wu, Feng Zhang

Article Number: 227 Published online on: 11 September 2020
Open Access

MicroRNA‑615 functions as a tumor suppressor in osteosarcoma through the suppression of HK2

Limin Sun, Peng Wang, Zhiqiang Zhang, Kai Zhang, Zheng Xu, Siyuan Li, Junsheng Mao

Article Number: 226 Published online on: 11 September 2020
Open Access

SUMO4 small interfering RNA attenuates invasion and migration via the JAK2/STAT3 pathway in non‑small cell lung cancer cells

Jin-Xiao Liang, Wei Gao, Xiao-Wei Zeng, Guo-Ping  Cheng, Lei Cai, Kai-Yi Tao, Xun Yang

Article Number: 225 Published online on: 11 September 2020
Open Access

Circulating microRNAs and their role in the immune response in triple‑negative breast cancer (Review)

Patricia Piña‑Sánchez, Hilda-Alicia Valdez‑Salazar, Martha-Eugenia Ruiz‑Tachiquín

Article Number: 224 Published online on: 11 September 2020
Open Access

MicroRNA‑3690 promotes cell proliferation and cell cycle progression by altering DKK3 expression in human thyroid cancer

Fei Shen, Xiao-Xiong Gan, Xing-Yan Deng, Jian-Hua Feng, Wen-Song Cai, Liang Shen, Huan-Qing Xiao, Bo Xu

Article Number: 223 Published online on: 10 September 2020
Open Access

[Retracted] Stem cell transplantation during cancer (Review)

Xiao-Ying Zhang, Pei-Ying Zhang

Article Number: 222 Published online on: 10 September 2020
Open Access

Role of TG2 and TGF‑β1 in the pathogenesis of human breast cancer

Hai-Cheng Gao, Yan-Zhi Huang, Yu-Qi Liu, Yan Chen, Zhe-Ηui Wang, Guang-Hao Yin

Article Number: 221 Published online on: 10 September 2020
Open Access

[Retracted] Combinations in multimodality treatments and clinical outcomes during cancer (Review)

Xiao-Ying Zhang, Pei-Ying Zhang

Article Number: 220 Published online on: 09 September 2020

IMPDH2 promotes cell proliferation and epithelial‑mesenchymal transition of non‑small cell lung cancer by activating the Wnt/β‑catenin signaling pathway

Hao Xu, Hongda Ma, Lifen Zha, Qian Li, Guanghui Yang, Huiming Pan, Xiangping Fei, Xingxiang Xu, Chen Xing, Ladi Zhang

Article Number: 219 Published online on: 09 September 2020
Open Access

[Corrigendum] DR2 blocker thioridazine: A promising drug for ovarian cancer therapy

Min Yong, Tinghe Yu, Si Tian, Shuaibin Liu, Jiao Xu, Jianguo Hu, Lina Hu

Article Number: 218 Published online on: 09 September 2020
Open Access

Analysis of key genes and pathways in breast ductal carcinoma in situ

Min Wu, Hongmei Zhao

Article Number: 217 Published online on: 09 September 2020
Open Access

Reduced IκBα promotes hepatocellular carcinoma cell proliferation and migration via regulation of NF‑κB/Erbin axis

Ye Tan, Xiao-Tong Lin, Yuan-Deng Luo, Jie Zhang, Lei Fang, Yan-Yin Zhu, Hong-Qiang Yu, Ling Shuai, Yan Jiang, Lei-Da Zhang, Ping Bie, Chuan-Ming Xie

Article Number: 216 Published online on: 09 September 2020
Open Access

MicroRNA‑4485 ameliorates severe influenza pneumonia via inhibition of the STAT3/PI3K/AKT signaling pathway

Longfei Guo, Quanhong Wang, Dongquan Zhang

Article Number: 215 Published online on: 09 September 2020
Open Access

Identification of hub genes associated with esophageal cancer progression using bioinformatics analysis

Jiangfen Li, Yufang Xie, Xueli Wang, Chenhao Jiang, Xin Yuan, Anzhi Zhang, Lan Yang, Chunxia Liu, Hong Zou, Feng Li, Jianming Hu

Article Number: 214 Published online on: 09 September 2020

Expression levels and clinical significance of miR‑203 and miR‑133b in laryngeal carcinoma

Na Zhao, Hongjun Liu, Aifen Zhang, Min Wang

Article Number: 213 Published online on: 08 September 2020
Open Access

ERCC overexpression associated with a poor response of cT4b colorectal cancer with FOLFOX‑based neoadjuvant concurrent chemoradiation

Ming-Yii Huang, Hsin-Hua Lee, Ching-Wen Huang, Chun-Ming  Huang, Cheng-Jen Ma, Tzu-Chieh Yin, Hsiang-Lin Tsai, Chee-Yin  Chai, Yi-Ting Chen, Jaw-Yuan Wang

Article Number: 212 Published online on: 08 September 2020
Open Access

High ADAMTS18 expression is associated with poor prognosis in stomach adenocarcinoma

Kaiyuan Jiang, Lei Li, Yubo Xie, Dongyi Xie, Qiang Xiao

Article Number: 211 Published online on: 08 September 2020
Open Access

MicroRNA‑150 suppresses p27Kip1 expression and promotes cell proliferation in HeLa human cervical cancer cells

Wataru Oboshi, Keisuke Hayashi, Hiroaki Takeuchi, Katsuhide Ikeda, Yoshitaka Yamaguchi, Asako Kimura, Takehiro Nakamura, Nobuyasu Yukimasa

Article Number: 210 Published online on: 08 September 2020
Open Access

Potential biomarkers Ang II/AT1R and S1P/S1PR1 predict the prognosis of hepatocellular carcinoma

Yuanyuan Ji, Haiyan Chen, Wei Gow, Li Ma, Yaofeng Jin, Bo Hui, Zhengan Yang, Zhidong Wang

Article Number: 208 Published online on: 08 September 2020

Progress of immune checkpoint LAG‑3 in immunotherapy (Review)

Chanchan Shan, Xing Li, Jian Zhang

Article Number: 207 Published online on: 08 September 2020
Open Access

Effects of hyperinsulinemia on acquired resistance to epidermal growth factor receptor‑tyrosine kinase inhibitor via the PI3K/AKT pathway in non‑small cell lung cancer cells in vitro

Hsin-Yi Chiu, Chi-Ming Chiang, Szu-Peng Yeh, De-Shien Jong, Leang-Shin Wu, Hung-Chang Liu, Chih-Hsien Chiu

Article Number: 206 Published online on: 08 September 2020
Open Access

Mutational analysis of extranodal marginal zone lymphoma using next generation sequencing

Seok Jae Huh, Sung Yong Oh, Suee Lee, Ji Hyun Lee, Sung Hyun Kim, Min Kyung Pak, Hyo-Jin Kim

Article Number: 205 Published online on: 08 September 2020

A prognosis‑predictive nomogram of ovarian cancer with two immune‑related genes: CDC20B and PNPLA5

Han Lin, Jiamin Wang, Xiaohui Wen, Qidan Wen, Shiya Huang, Zhefen Mai, Lingjing Lu, Xingyan Liang, Haixia Pan, Shuna Li, Yuhong He, Hongxia Ma

Article Number: 204 Published online on: 08 September 2020
Open Access

RRBP1 is highly expressed in bladder cancer and is associated with migration and invasion

Mingshuai Wang, Sai Liu, Bolin Zhou, Jianwen Wang, Hao Ping, Nianzeng Xing

Article Number: 203 Published online on: 08 September 2020
Open Access

Long non‑coding RNA BACE1‑AS is an independent unfavorable prognostic factor in liver cancer

Yuanyuan Nie, Yanqing Li, Yanhui Xu, Yan Jiao, Wei Li

Article Number: 202 Published online on: 08 September 2020
Open Access

Morphological and functional alterations of the prostate tissue during clinical progression in hormonally‑naïve, hormonally‑treated and castration‑resistant patients with metastatic prostate cancer

Michal Korček, Monika Sekerešová, Alexander V. Makarevich, Helena Gavurová, Lucia Olexíková, Juraj Pivko, Lenka Barreto

Article Number: 201 Published online on: 08 September 2020
Open Access

Negative regulation between the expression levels of receptor for hyaluronic acid‑mediated motility and hyaluronan leads to cell migration in pancreatic cancer

Xiao-Bo Cheng, Shuwen Wang, Hua Yang, Hanxing Tong, Guodong Shi, Lili Wu, Lei Shi, Hongwei Li, Songtao Ren, Yuhong Zhou, Norihiro Sato, Jian Zhou

Article Number: 199 Published online on: 04 September 2020
Open Access

MZB1 expression indicates poor prognosis in estrogen receptor‑positive breast cancer

Manabu Watanabe, Masahiro Shibata, Takahiro Inaishi, Takahiro Ichikawa, Ikumi Soeda, Noriyuki Miyajima, Yuko Takano, Dai Takeuchi, Nobuyuki Tsunoda, Mitsuro Kanda, Toyone Kikumori, Yasuhiro Kodera, Masato Nagino

Article Number: 198 Published online on: 04 September 2020
Open Access

High glypican‑1 expression is a prognostic factor for predicting a poor clinical prognosis in patients with hepatocellular carcinoma

Guoyong Chen, Hao Wu, Lei Zhang, Sidong Wei

Article Number: 197 Published online on: 04 September 2020
Open Access

[Retracted] Scorpion venoms in gastric cancer (Review)

Xiao-Ying Zhang, Pei-Ying Zhang

Article Number: 196 Published online on: 04 September 2020
Open Access

[Retracted] Receptor tyrosine kinases in carcinogenesis (Review)

Xiao-Ying Zhang, Pei-Ying Zhang

Article Number: 195 Published online on: 04 September 2020
Open Access

Systemic thromboembolism from a misdiagnosed non‑bacterial thrombotic endocarditis in a patient with lung cancer: A case report

Fabiana Perrone, Andrea Biagi, Francesco Facchinetti, Francesca Bozzetti, Andrea Ramelli, Antonella Vezzani, Tullio Manca, Letizia Gnetti, Maria Majori, Veronica Alfieri, Marcello Tiseo

Article Number: 194 Published online on: 03 September 2020
Open Access

Membrane mesothelin expression positivity is associated with poor clinical outcome of luminal‑type breast cancer

Takafumi Suzuki, Yoji Yamagishi, Takahiro Einama, Tomomi Koiwai, Tamio  Yamasaki, Makiko Fukumura‑koga, Yusuke Ishibashi, Yasuhiro  Takihata, Takehiro Shiraishi, Yoichi Miyata, Toshimitsu Iwasaki, Eiji Shinto, Kimiya  Sato, Hideki Ueno, Junji Yamamoto, Yoji Kishi, Hitoshi Tsuda

Article Number: 193 Published online on: 03 September 2020
Open Access

A novel definition of microvessel density in renal cell carcinoma: Angiogenesis plus vasculogenic mimicry

Yanyuan Wu, Kun Du, Wenbin Guan, Di Wu, Haixiao Tang, Ning Wang, Jun Qi, Zhengqin Gu, Junyao Yang, Jie Ding

Article Number: 192 Published online on: 03 September 2020
Open Access

Analysis of the expression levels and clinical value of miR‑365 and miR‑25 in serum of patients with non‑small cell lung cancer

Dongxuan Huang, Wenfang Ou, Huifen Tong, Ming Peng, Yamei Ou, Zeqing Song

Article Number: 191 Published online on: 03 September 2020
Open Access

Integrative assessment of clinicopathological parameters and the expression of PD‑L1, PD‑L2 and PD‑1 in tumor cells of retroperitoneal sarcoma

Makito Miyake, Yuki Oda, Nobutaka Nishimura, Yosuke Morizawa, Sayuri  Ohnishi, Kinta  Hatakeyama, Tomomi Fujii, Shunta Hori, Daisuke  Gotoh, Yasushi Nakai, Satoshi  Anai, Kazumasa Torimoto, Shinji  Tsukamoto, Hiromasa Fujii, Akira Kido, Kanya  Honoki, Yoshiaki  Matsumura, Eijiro Okajima, Nobumichi Tanaka, Kiyohide Fujimoto

Article Number: 190 Published online on: 03 September 2020
Open Access

Association between excessive chronic iodine exposure and the occurrence of papillary thyroid carcinoma

Fengyan Huang, Wei Cong, Juan Xiao, Yong Zhou, Maosong Gong, Jingfu Sun, Liqun  Shan, Qiang Xiao, Lihua Wang, Jianing Liu, Zhigang Yu, Hongying Jia

Article Number: 189 Published online on: 03 September 2020
Open Access

Long non‑coding RNAs lnc‑ANGPTL1‑3:3 and lnc‑GJA10‑12:1 present as regulators of sentinel lymph node metastasis in breast cancer

Desheng Sun, Jieyu Zhong, Wei Wei, Li Liu, Jun Liu, Xiaona Lin

Article Number: 188 Published online on: 03 September 2020
Open Access

Whole‑transcriptome sequencing profiling identifies functional and prognostic signatures in patients with PTPRZ1‑MET fusion‑negative secondary glioblastoma multiforme

Bao‑Shi Chen, Kuan-Yu Wang, Shu-Qing Yu, Chuan-Bao Zhang, Guan-Zhang Li, Zhi-Liang Wang, Zhao-Shi Bao

Article Number: 187 Published online on: 03 September 2020
Open Access

Knockdown of SAR1B suppresses proliferation and induces apoptosis of RKO colorectal cancer cells

Yong Lu, Shen-Kang Zhou, Rui Chen, Liang-Xian Jiang, Lei-Lei Yang, Tie-Nan Bi

Article Number: 186 Published online on: 03 September 2020
Open Access

[Retracted] Recent perspectives of epithelial ovarian carcinoma (Review)

Xiao-Ying Zhang, Pei-Ying Zhang

Article Number: 185 Published online on: 01 September 2020
Open Access

[Retracted] Genetics and epigenetics of melanoma (Review)

Xiao-Ying Zhang, Pei-Ying Zhang

Article Number: 184 Published online on: 01 September 2020

Analysis of diagnostic and prognostic value of lncRNA MEG3 in cervical cancer

Shuqiong Wan, Huanqiu Zhao

Article Number: 183 Published online on: 31 August 2020
Open Access

Expression of SLC17A9 in hepatocellular carcinoma and its clinical significance

Jingdong Wu, Yongfei Yang, Jiansheng Song

Article Number: 182 Published online on: 31 August 2020
Open Access

Linalool inhibits the growth of human T cell acute lymphoblastic leukemia cells with involvement of the MAPK signaling pathway

Xubo Gong, Baiyong Wang, Lijuan Yan, Xiaoya Lu, Xiaoying Zhao

Article Number: 181 Published online on: 31 August 2020

Significance of age‑associated quality of life in patients with stage IV breast cancer who underwent endocrine therapy in Japan

Koji Takada, Shinichiro Kashiwagi, Yuka Asano, Wataru Goto, Tamami  Morisaki, Katsuyuki Takahashi, Masatsune Shibutani, Ryosuke Amano, Tsutomu  Takashima, Shuhei Tomita, Kosei Hirakawa, Masaichi Ohira

Article Number: 180 Published online on: 31 August 2020
Open Access

Sterically stabilized liposomes targeting P21 (RAC1) activated kinase‑1 and secreted phospholipase A2 suppress prostate cancer growth and metastasis

Arti Verma, Wided Najahi‑Missaoui, Brian S. Cummings, Payaningal R. Somanath

Article Number: 179 Published online on: 31 August 2020
Open Access

Antitumor effects of ribavirin in combination with TMZ and IFN‑β in malignant glioma cells

Yushi Ochiai, Koichiro Sumi, Emiko Sano, Sodai Yoshimura, Shun Yamamuro, Akiyoshi Ogino, Takuya Ueda, Yutaka Suzuki, Tomohiro Nakayama, Hiroyuki Hara, Yoichi Katayama, Atsuo Yoshino

Article Number: 178 Published online on: 31 August 2020
Open Access

High expression of eIF4A2 is associated with a poor prognosis in esophageal squamous cell carcinoma

Shanshan Lyu, Jiabin Lu, Wendan Chen, Weiye Huang, Haoqi Huang, Shaoyan Xi, Shumei Yan

Article Number: 177 Published online on: 31 August 2020
Open Access

The value of 18F‑FDG PET/CT in the prediction of clinical outcomes of patients with acute leukemia treated with allogeneic hematopoietic stem cell transplantation

Zixuan Zhao, Yeye Zhou, Jing Wang, Tongtong Zhang, Jihui Li, Bin Zhang, Qingru Li, Shengming Deng

Article Number: 175 Published online on: 31 August 2020
Open Access

TMEM206 is a potential prognostic marker of hepatocellular carcinoma

Li Zhang, Shi-Yi Liu, Xiao Yang, Yan-Qing Wang, Yan-Xiang Cheng

Article Number: 174 Published online on: 28 August 2020

Associations of MTA1 expression with CT features, pathology and prognosis of elderly patients with non-small cell lung cancer

Ning Yang, Chuanming Li, Xiao Han, Zhihua Feng, Feng Qiu, Junqing Han

Article Number: 172 Published online on: 28 August 2020
Open Access

Bufalin attenuates triple‑negative breast cancer cell stemness by inhibiting the expression of SOX2/OCT4

Fei Chen, Li Zhu, Junyan Hu, Shujun Jiang, Hui Liu, Jie Zheng, Jiandong Wang, Feng Wang, Zhe Li

Article Number: 171 Published online on: 28 August 2020
Open Access

Ursolic acid inhibits the invasiveness of A498 cells via NLRP3 inflammasome activation

Yuan-Min Chen, Bi-Xia Tang, Wei-Yong Chen, Ming-Sheng Zhao

Article Number: 170 Published online on: 28 August 2020
Open Access

Resveratrol inhibits proliferation and promotes apoptosis via the androgen receptor splicing variant 7 and PI3K/AKT signaling pathway in LNCaP prostate cancer cells

Mushi Ye, Huanshu Tian, Shanhong Lin, Jierong Mo, Zhuo Li, Xiaojun Chen, Jianjun Liu

Article Number: 169 Published online on: 27 August 2020
Open Access

Amentoflavone triggers cell cycle G2/M arrest by interfering with microtubule dynamics and inducing DNA damage in SKOV3 cells

Jinli Zhang, Aiguo Li, Hanjing Sun, Xifeng Xiong, Shengnan Qin, Pengzhen Wang, Libing Dai, Zhi Zhang, Xiaojian Li, Zhihe Liu

Article Number: 168 Published online on: 27 August 2020
Open Access

Emodin alleviates gemcitabine resistance in pancreatic cancer by inhibiting MDR1/P‑glycoprotein and MRPs expression

Hongchun Guo, Feng Liu, Shuguang Yang, Tao Xue

Article Number: 167 Published online on: 27 August 2020
Open Access

Monascin accelerates anoikis in circulating tumor cells and prevents breast cancer metastasis

Kung‑Yen Chen, Jui-An Lin, Han-Yun Yao, An-Chih Hsu, Yu‑Ting Tai, Bing‑Ying Ho

Article Number: 166 Published online on: 27 August 2020
Open Access

Y‑box binding protein 1 acts as a negative regulator of stearoyl CoA desaturase 1 in clear cell renal cell carcinoma

Eric Jeffords, Samuel Freeman, Breanna Cole, Kate Root, Thierry Chekouo, Richard G. Melvin, Lynne Bemis, Glenn E. Simmons Jr

Article Number: 165 Published online on: 26 August 2020
Open Access

lncRNA MALAT1 promotes cell proliferation and invasion by regulating the miR‑101/EZH2 axis in oral squamous cell carcinoma

Lei Xiao, Weiping Wang, Jingjing Zhao, Hongyan Xu, Shaozhen Li, Xiuhua Yang

Article Number: 164 Published online on: 26 August 2020
Open Access

[Corrigendum] Clinical outcomes in primary scalp angiosarcoma

Yong Zhang, Yanwen Yan, Ming Zhu, Cheng Chen, Nanhang Lu, Fazhi Qi, Jiaqi Liu

Article Number: 163 Published online on: 26 August 2020
Open Access

Potential relationship between Sirt3 and autophagy in ovarian cancer (Review)

Yuchuan Shi, Runhua He, Yu Yang, Yu He, Lei Zhan, Bing Wei

Article Number: 162 Published online on: 26 August 2020
Open Access

Nuclear receptor FXR impairs SK‑Hep‑1 cell migration and invasion by inhibiting the Wnt/β‑catenin signaling pathway

Qianqian Li, Ningbo Li, Yeting Zeng, Xinrui Wang, Jie Li, Hongying Su, Meiqin Gao, Xiongfei Huang

Article Number: 161 Published online on: 26 August 2020
Open Access

MicroRNA‑23b‑3p promotes pancreatic cancer cell tumorigenesis and metastasis via the JAK/PI3K and Akt/NF‑κB signaling pathways

Yunan Zhang, Dayang Chen, Guoqiang Zhang, Xiongbo Wu, Liangyun Zhou, Yexin Lin, Junli Ding, Fangmei An, Qiang Zhan

Article Number: 160 Published online on: 26 August 2020

Mechanism of transmembrane and coiled‑coil domain 1 in the regulation of proliferation and migration of A549 cells

Chen Yang, Yuan Wang, Jian-Qi Bai, Jing-Ru Zhang, Pei-Yan Hu, Yan Zhu, Qin Ouyang, Hong-Mei Su, Qiu-Yue Li, Ping Zhang

Article Number: 159 Published online on: 26 August 2020
Open Access

Epithelial‑to‑mesenchymal transition markers are differentially expressed in epithelial cancer cell lines after everolimus treatment

Bryan Ôrtero Perez Gonçalves, Warne Pedro de Andrade, Letícia da Conceição Braga, Sílvia Ligório Fialho, Luciana Maria Silva

Article Number: 158 Published online on: 25 August 2020
Open Access

[Retracted] Long non‑coding RNA TTN‑AS1 promotes breast cancer cell migration and invasion via sponging miR‑140‑5p

Jie Xue, Zhixia Zhang, Xiaona Li, Qingfang Ren, Qinghua Wang

Article Number: 157 Published online on: 25 August 2020

Therapeutic effect of metformin in the treatment of endometrial cancer (Review)

Nan Mu, Tingting Xu, Mingxiao Gao, Mei Dong, Qing Tang, Li Hao, Guiqing Wang, Zenghui Li, Wenshuang Wang, Ying Yang, Jianqing Hou

Article Number: 156 Published online on: 24 August 2020
Open Access

Association between MDR1 polymorphisms and XELIRI and XELOX chemoresistance in Saudi patients with colorectal cancer

Ayat B. Al‑Ghafari, Areej M. Al Qahtani, Suzan N. Alturki, Huda A. Al Doghaither, Ekramy M. Elmorsy, Hanaa M. Tashkandi, Atlal M. Abusanad, Shadi S. Alkhayyat, Ulfat M. Omar, Ahmed A. Zeeneldin

Article Number: 155 Published online on: 24 August 2020

Cyclin D1 overexpression enhances chemosensitivity to TPF chemotherapeutic agents via the caspase‑3 pathway in oral cancer

Yong-Jie Hu, Wen‑Wen Sun, Tong-Chao Zhao, Ying Liu, Dong-Wang Zhu, Li-Zhen Wang, Jiang Li, Chen-Ping Zhang, Zhi-Yuan Zhang, Lai-Ping Zhong

Article Number: 154 Published online on: 24 August 2020
Open Access

The histone methyltransferase SMYD2 is a novel therapeutic target for the induction of apoptosis in ovarian clear cell carcinoma cells

Machiko Kojima, Kenbun Sone, Katsutoshi Oda, Ryuji Hamamoto, Syuzo Kaneko, Shinya Oki, Asako Kukita, Akira Kawata, Harunori Honjoh, Yoshiko Kawata, Tomoko Kashiyama, Masakazu Sato, Ayumi Taguchi, Yuichiro Miyamoto, Michihiro Tanikawa, Tetsushi Tsuruga, Kazunori Nagasaka, Osamu Wada‑Hiraike, Yutaka Osuga, Tomoyuki Fujii

Article Number: 153 Published online on: 24 August 2020
Open Access

α‑enolase is highly expressed in liver cancer and promotes cancer cell invasion and metastasis

Lihong Zhang, Tao Lu, Ye Yang, Liangfeng Hu

Article Number: 152 Published online on: 24 August 2020
Open Access

Pro‑apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro

Ilaria Lampronti, Daniele Simoni, Riccardo Rondanin, Riccardo Baruchello, Chiara Scapoli, Alessia Finotti, Monica Borgatti, Chiara Tupini, Roberto Gambari

Article Number: 151 Published online on: 24 August 2020
Open Access

Comparative effectiveness of surgery and radiotherapy for survival of patients with clinically localized prostate cancer: A population‑based coarsened exact matching retrospective cohort study

Masato Yasui, Masahiko Sakaguchi, Ryousuke Jikuya, Sohgo  Tsutsumi, Tomoyuki Tatenuma, Go Noguchi, Susumu Umemoto, Kayako Katayama, Hiroto Narimatsu, Hiroji Uemura, Takeshi Kishida

Article Number: 150 Published online on: 24 August 2020
Open Access

Prognostic values of EDNRB in triple‑negative breast cancer

Shaoqing Liu, Jingyang Zhang, Jiujun Zhu, Dechuang Jiao, Zhenzhen Liu

Article Number: 149 Published online on: 24 August 2020
Open Access

Effect of sodium butyrate on ABC transporters in lung cancer A549 and colorectal cancer HCT116 cells

Bin Shi, Fang‑Fang Xu, Cai‑Ping Xiang, Ru Jia, Chun-Hong Yan, Se-Qing Ma, Ning Wang, An-Jiao Wang, Ping Fan

Article Number: 148 Published online on: 24 August 2020
Open Access

Maternal embryonic leucine zipper kinase: A novel biomarker and a potential therapeutic target in lung adenocarcinoma

Shengsong Chen, Zhanpeng Lu, Xiaoyong Chen, Xiya Wu, Hongying Tu, Lingling Yu, Zuke Xiao

Article Number: 147 Published online on: 24 August 2020
Open Access

DEPDC1B promotes migration and invasion in pancreatic ductal adenocarcinoma by activating the Akt/GSK3β/Snail pathway

Xu Liu, Tong Li, Xinyang Huang, Wei Wu, Juanjuan Li, Lumin  Wei, Yuting Qian, Hui Xu, Qi Wang, Lifu Wang

Article Number: 146 Published online on: 24 August 2020

Identification and validation of core genes for serous ovarian adenocarcinoma via bioinformatics analysis

Ruru Zhu, Jisen Xue, Huijun Chen, Qian Zhang

Article Number: 145 Published online on: 21 August 2020
Open Access

Clinical experience of 23 cases of adenoid cystic carcinoma of the external auditory canal

Xiaojun Jiang, Lifeng Jia, Xueyuan Zhang, Cheng Zhong, Feng Tang, Xiaoling Chen, Wei Yuan

Article Number: 144 Published online on: 21 August 2020
Open Access

Prognostic effects of the expression of inhibitor of DNA‑binding family members on patients with lung adenocarcinoma

Xiaomin Lu, Lili Shao, Ye Qian, Yan Zhang, Yongsheng Wang, Liyun Miao, Zhixiang Zhuang

Article Number: 143 Published online on: 21 August 2020
Open Access

Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu

Article Number: 142 Published online on: 21 August 2020
Open Access

Antitumor effects and molecular mechanisms of action of natural products in ovarian cancer (Review)

Yun-Bo Yan, Qing Tian, Ji-Fang Zhang, Ying Xiang

Article Number: 141 Published online on: 20 August 2020
Open Access

Immunotyping of tumor‑infiltrating lymphocytes in triple‑negative breast cancer and genetic characterization

Gabriela Sofia Gomez‑Μacias, Guillermo Molinar‑Flores, Carlos A. Lopez‑Garcia, Sandra Santuario‑Facio, Horacio Decanini‑Arcaute, Javier Valero‑Elizondo, Victor Treviño‑Alvarado, Rocio Ortiz‑Lopez, Antonio Dono, Eduardo Esteban‑Zubero, Moises A. Alatorre‑Jimenez, Cynthia Villarreal Garza, Omar Peña‑Curiel, Servando Cardona‑Huerta

Article Number: 140 Published online on: 20 August 2020
Open Access

Biomarkers of immunotherapy in non‑small cell lung cancer (Review)

Lingling Wang, Yue Hu, Shengchao Wang, Jiali Shen, Xiaochen Wang

Article Number: 139 Published online on: 20 August 2020

Stem cell models for genetically predisposed colon cancer (Review)

Nitin Telang

Article Number: 138 Published online on: 20 August 2020
Open Access

ZBED1/DREF: A transcription factor that regulates cell proliferation (Review)

Yarong Jin, Ruilei Li, Zhiwei Zhang, Jinjin Ren, Xin Song, Gong Zhang

Article Number: 137 Published online on: 20 August 2020

New benzenesulphonohydrazide derivatives as potential antitumour agents

Łukasz Popiołek, Monika Gawrońska‑Grzywacz, Anna Berecka‑Rycerz, Kinga Paruch, Iwona Piątkowska‑Chmiel, Dorota Natorska‑Chomicka, Mariola Herbet, Anna Gumieniczek, Jarosław Dudka, Monika Wujec

Article Number: 136 Published online on: 02 September 2020
Open Access

[Erratum] Expression of ywhaz and gene regulation network in hepatocellular carcinoma

Yi Lin, Ling Sun, Xiaolei Ye

Article Number: 135 Published online on: 20 August 2020
Open Access

Effects of lncRNA TUSC7 on the malignant biological behavior of osteosarcoma cells via regulation of miR‑375

Lulu Wang, Jiankui Jiang, Guisen Sun, Panpan Zhang, Ya Li

Article Number: 133 Published online on: 20 August 2020
Open Access

Flurbiprofen suppresses the inflammation, proliferation, invasion and migration of colorectal cancer cells via COX2

Xiaobo Wang, Xuxing Ye, Yili Zhang, Feng Ji

Article Number: 132 Published online on: 20 August 2020
Open Access

PTPRA facilitates cancer growth and migration via the TNF‑α‑mediated PTPRA‑NF‑κB pathway in MCF‑7 breast cancer cells

Canfeng Lin, Shubo Xin, Xiaoguang Huang, Feiran Zhang

Article Number: 131 Published online on: 20 August 2020
Open Access

Cancer‑associated fibroblasts, matrix metalloproteinase‑9 and lymphatic vessel density are associated with progression from adenocarcinoma in situ to invasive adenocarcinoma of the lung

Cheng Chen, Wu-Jun Li, Jing-Jing Weng, Zhi-Jun Chen, Yuan-Yuan Wen, Tao Deng, Han-Bo Le, Yong-Kui Zhang, Bin-Jie Zhang

Article Number: 130 Published online on: 20 August 2020
Open Access

Genetic profiling of somatic alterations by Oncomine Focus Assay in Korean patients with advanced gastric cancer

Joonhong Park, Sang-Il Lee, Soyoung Shin, Jang Hee Hong, Han Mo Yoo, Jeong Goo Kim

Article Number: 129 Published online on: 20 August 2020
Open Access

PLAC8 inhibits oral squamous cell carcinogenesis and epithelial-mesenchymal transition via the Wnt/β-catenin and PI3K/Akt/GSK3β signaling pathways

Junlu Wu, Xuetao Wang, Anquan Shang, Giovanna Vella, Zujun Sun, Ping Ji, Dianyu Yang, Aiming Wan, Yiwen Yao, Dong Li

Article Number: 128 Published online on: 19 August 2020
Open Access

Low HOXC10 expression in liver cancer regulates proliferation via a mechanism involving miR‑221 and the MAPK signaling pathway

Kexin Ma, Chongyu Zhao, Kun Guo, Zhaoyu Fu, Chi Che, Bing Dong, Chong Pang, Shaoming Zhang, Wuguang Liu, Zexuan Yang, Rui Liang, Liming Wang

Article Number: 127 Published online on: 19 August 2020

Challenges surrounding postoperative adjuvant chemotherapy for T2N0 gastric cancer (Review)

Ke-Kang Sun, Qing-Hua Wang, Yong-You Wu

Article Number: 126 Published online on: 19 August 2020
Open Access

Application of the da Vinci surgical robot system in presacral nerve sheath tumor treatment

Feifei Pu, Zhicai Zhang, Zhaohui Chen, Kailin Cai, Baichuan Wang, Qiang Wu, Deyao Shi, Jianxiang Liu, Zengwu Shao

Article Number: 125 Published online on: 19 August 2020
Open Access

Long intergenic non‑protein coding RNA‑467 targets microRNA‑451a in human colorectal cancer

Yang Bai, Haiyan Wu, Bin Han, Ke Xu, Yuanqi Liu, Yin  Liu, Shikun Miao, Yuanyuan Zhang, Liming Zhou

Article Number: 124 Published online on: 19 August 2020
Open Access

Point mutation screening of tumor neoantigens and peptide‑induced specific cytotoxic T lymphocytes using The Cancer Genome Atlas database

Wanwen Wu, Ying Chen, Lan Huang, Wenjian Li, Changli Tao, Han Shen

Article Number: 123 Published online on: 19 August 2020
Journal Cover

November-2020
Volume 20 Issue 5

Print ISSN: 1792-1074
Online ISSN: 1792-1082

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