Journal Articles

Open Access

The role of pyruvate kinase M2 in anticancer therapeutic treatments (Review)

Qiongli Su, Shengping Luo, Qiuhong Tan, Jun Deng, Sichun Zhou, Mei Peng, Ting Tao, Xiaoping Yang

Pages: 5663-5672 Published online on: 02 October 2019

The roles of estrogen and estrogen receptors in gastrointestinal disease (Review)

Changmei Chen, Xiang Gong, Xiaoxu Yang, Xianhui Shang, Qian Du, Qiushi Liao, Rui Xie, Yuanshou Chen, Jingyu Xu

Pages: 5673-5680 Published online on: 11 October 2019
Open Access

Use of immunotherapy in the treatment of gastric cancer (Review)

Luhong Yang, Yanxia Wang, Huafeng Wang

Pages: 5681-5690 Published online on: 30 September 2019
Open Access

Role of apoptosis repressor with caspase recruitment domain (ARC) in cancer (Review)

Zhongjie Yu, Qi Li, Yi An, Xiatian Chen, Ziqian Liu, Zhe Li, Jinning Gao, Lynn Htet Htet Aung, Peifeng Li

Pages: 5691-5698 Published online on: 11 October 2019
Open Access

Insights on CXC chemokine receptor 2 in breast cancer: An emerging target for oncotherapy (Review)

Fengzhu Guo, Lang Long, Jiantao Wang, Yuyi Wang, Yanyang Liu, Li Wang, Feng Luo

Pages: 5699-5708 Published online on: 03 October 2019
Open Access

Claudin‑1 silencing increases sensitivity of liver cancer HepG2 cells to 5‑fluorouracil by inhibiting autophagy

Hui Tong, Tao Li, Weihua Qiu, Zhecheng Zhu

Pages: 5709-5716 Published online on: 08 October 2019
Open Access

Predictive significance of T cell subset changes during ex vivo generation of adoptive cellular therapy products for the treatment of advanced non‑small cell lung cancer

Lefu Huang, Guoliang Qiao, Michael A. Morse, Xiaoli Wang, Xinna Zhou, Jiangping Wu, Amy Hobeika, Jun Ren, Herbert K. Lyerly

Pages: 5717-5724 Published online on: 04 October 2019
Open Access

PACAP and PAC1 receptor expression in pancreatic ductal carcinoma

Sandor Ferencz, Dora Reglodi, Balint Kaszas, Attila Bardosi, Denes Toth, Zsofia Vekony, Viktoria Vicena, Oszkar Karadi, Dezso Kelemen

Pages: 5725-5730 Published online on: 08 October 2019
Open Access

GABRQ expression is a potential prognostic marker for patients with clear cell renal cell carcinoma

Dongjun Lee, Mihyang Ha, Chae Mi Hong, Jayoung Kim, Su Min Park, Dongsu Park, Dong Hyun Sohn, Ho Jin Shin, Hak‑Sun Yu, Chi Dae Kim, Chi‑Dug Kang, Myoung‑Eun Han, Sae‑Ock Oh, Yun Hak Kim

Pages: 5731-5738 Published online on: 04 October 2019
Open Access

KIFC1 promotes the proliferation of hepatocellular carcinoma in vitro and in vivo

Xing Wang, Meng Wang, Xing‑Yue Li, Jian Li, Dian‑Peng Zhao

Pages: 5739-5746 Published online on: 14 October 2019
Open Access

Impact of antiretroviral drugs on PD‑L1 expression and copy number gains with clinical outcomes in HIV‑positive and ‑negative locally advanced cervical cancers

Kongsak Loharamtaweethong, Songkhun Vinyuvat, Jidapa Thammasiri, Sakchai Chitpakdee, Chalermpak Supakatitham, Napaporn Puripat

Pages: 5747-5758 Published online on: 04 October 2019
Open Access

Interleukin 1 receptor antagonist gene variable number of tandem repeats polymorphism and cutaneous melanoma

Sabina Cauci, Cinzia Buligan, Francesco Rocchi, Ilaria Salvador, Luigi Xodo, Giuseppe Stinco

Pages: 5759-5768 Published online on: 25 September 2019
Open Access

Identification of the lncRNA‑miRNA‑mRNA network associated with gastric cancer via integrated bioinformatics analysis

Xiao‑Yu Ma, Yu Ma, Huan Zhou, Hui‑Jing Zhang, Ming‑Jun Sun

Pages: 5769-5784 Published online on: 25 September 2019
Open Access

A nomogram to predict vascular invasion before resection of colorectal cancer

Weishun Xie, Jungang Liu, Xiaoliang Huang, Guo Wu, Franco Jeen, Shaomei Chen, Chuqiao Zhang, Wenkang Yang, Chan Li, Zhengtian Li, Lianying Ge, Weizhong Tang

Pages: 5785-5792 Published online on: 30 September 2019
Open Access

Celecoxib suppresses lipopolysaccharide‑stimulated oral squamous cell carcinoma proliferation in vitro and in vivo

Hisato Yoshida, Hitoshi Yoshimura, Shinpei Matsuda, Satoshi Yamamoto, Masahiro Ohmori, Keiichi Ohta, Takashi Ryoke, Hayato Itoi, Tamotsu Kiyoshima, Motohiro Kobayashi, Kazuo Sano

Pages: 5793-5800 Published online on: 10 October 2019
Open Access

Expression of the Sonic Hedgehog pathway components in clear cell renal cell carcinoma

Anna Kotulak‑Chrzaszcz, Jakub Klacz, Marcin Matuszewski, Zbigniew Kmiec, Piotr M. Wierzbicki

Pages: 5801-5810 Published online on: 25 September 2019
Open Access

High efficacy and safety of VTD as an induction protocol in patients with newly diagnosed multiple myeloma eligible for high dose therapy and autologous stem cell transplantation: A report of the Polish Myeloma Study Group

Iwona Hus, Joanna Mańko, Dariusz Jawniak, Artur Jurczyszyn, Grzegorz Charliński, Katarzyna Poniewierska‑Jasak, Lidia Usnarska‑Zubkiewicz, Mateusz Sawicki, Agnieszka Druzd‑Sitek, Alina Świderska, Anna Kopińska, Norbert Grząśko, Małgorzata Raźny, Aleksandra Wędłowska, Aleksander Perzyński, Aleksandra Gałązka, Dominik Dytfeld, Tadeusz Kubicki, Marek Rodzaj, Anna Waszczuk‑Gajda, Joanna Drozd‑Sokołowska, Bartłomiej Pogłódek, Anna Pasternak, Monika Długosz‑Danecka, Agnieszka Szymczyk, Anna Dmoszyńska

Pages: 5811-5820 Published online on: 27 September 2019
Open Access

Screening of core genes and pathways in breast cancer development via comprehensive analysis of multi gene expression datasets

Jie Bai, Xiaoyu Zhang, Xiaoning Kang, Lijun Jin, Peng Wang, Zunyi Wang

Pages: 5821-5830 Published online on: 11 October 2019
Open Access

DNA methylation profiling analysis identifies a DNA methylation signature for predicting prognosis and recurrence of lung adenocarcinoma

Rui Wang, Hong Zhu, Mingxia Yang, Chunrong Zhu

Pages: 5831-5842 Published online on: 30 September 2019
Open Access

Jumonji domain‑containing protein 6 functions as a marker of head and neck squamous cell carcinoma at advanced stage with no effect on prognosis

Bing Guo, Lei Wang, Xingjun Qin, Yi Shen, Chunyue Ma

Pages: 5843-5852 Published online on: 30 September 2019
Open Access

Expression of miR-23a and miR-135 and tumor markers in gastric cancer patients and the significance in diagnosis

Likui Yin, Guangxiao Xu, Yuntao Zhu, Yongqiang Wang

Pages: 5853-5858 Published online on: 01 October 2019
Open Access

Identification of key genes and evaluation of clinical outcomes in lung squamous cell carcinoma using integrated bioinformatics analysis

Yangfeng Shi, Yeping Li, Chao Yan, Hua Su, Kejing Ying

Pages: 5859-5870 Published online on: 30 September 2019
Open Access

Hypoxia modifies the polarization of macrophages and their inflammatory microenvironment, and inhibits malignant behavior in cancer cells

Xixian Ke, Cheng Chen, Yongxiang Song, Qingyong Cai, Jian Li, Yang Tang, Xu Han, Wendong Qu, Anping Chen, Hui Wang, Gang Xu, Daxing Liu

Pages: 5871-5878 Published online on: 03 October 2019
Open Access

Data mining of the expression and regulatory role of BCAT1 in hepatocellular carcinoma

Haifan Zou, Minjun Liao, Wentao Xu, Renzhi Yao, Weijia Liao

Pages: 5879-5888 Published online on: 30 September 2019
Open Access

Accelerated elimination of human cancer cells by a CD40 agonist antibody combined with a PD‑1 antagonist in CD4‑depleted mice

Soon‑Hyun Ahn, Joo Yeon Choi, Seong Dong Kim, Sung Joon Park, Hyojin Kim

Pages: 5889-5896 Published online on: 14 October 2019
Open Access

Dendritic cells loaded with CD44+ CT‑26 colon cell lysate evoke potent antitumor immune responses

Changhao Fu, Ning Zhou, Yuanyuan Zhao, Jinyue Duan, Hao Xu, Yi Wang

Pages: 5897-5904 Published online on: 02 October 2019
Open Access

A nomogram for the prediction of overall survival in patients with stage II and III non‑small cell lung cancer using a population‑based study

Yi Liao, Xue Wang, Ping Zhong, Guofang Yin, Xianming Fan, Chengliang Huang

Pages: 5905-5916 Published online on: 10 October 2019
Open Access

Clinical value of ultrasonic imaging in diagnosis of hypopharyngeal cancer with cervical lymph node metastasis

Guzi Wang, Xiaoguang Li, Li Li, Dayu Liu, Ruijie Sun, Qiu Zhang, Chenchen Geng, Haitong Gong, Xiaoqian Gao

Pages: 5917-5922 Published online on: 30 September 2019
Open Access

lncRNA AWPPH promotes the migration and invasion of glioma cells by activating the TGF‑β pathway

Bin Dai, Zhiyong Xiao, Beibei Mao, Guangtong Zhu, Hui Huang, Feng Guan, Haiyang Su, Zhenyang Lin, Weicheng Peng, Zhiqiang Hu

Pages: 5923-5929 Published online on: 25 September 2019
Open Access

JMJD3 promotes the epithelial‑mesenchymal transition and migration of glioma cells via the CXCL12/CXCR4 axis

Shuang Zou, Dongchen Zhang, Zhongwei Xu, Xiaochang Wen, Yan Zhang

Pages: 5930-5940 Published online on: 09 October 2019
Open Access

Functional impact of the long non‑coding RNA MEG3 deletion by CRISPR/Cas9 in the human triple negative metastatic Hs578T cancer cell line

Carlos Deocesano‑Pereira, Raquel Arminda Carvalho Machado, Henrique Cesar de Jesus‑Ferreira, Thiago Marchini, Tulio Felipe Pereira, Ana Claudia Oliveira Carreira, Mari Cleide Sogayar

Pages: 5941-5951 Published online on: 08 October 2019
Open Access

Abnormal accumulation of p53 predicts radioresistance leading to poor survival in patients with endometrial carcinoma

Azusa Akiyama, Takeo Minaguchi, Kaoru Fujieda, Yoshihiko Hosokawa, Keiko Nishida, Ayumi Shikama, Nobutaka Tasaka, Manabu Sakurai, Hiroyuki Ochi, Toyomi Satoh

Pages: 5952-5958 Published online on: 30 September 2019
Open Access

Five extracellular matrix‑associated genes upregulated in oral tongue squamous cell carcinoma: An integrated bioinformatics analysis

Pingping Zhong, Liya Liu, Aling Shen, Zhongxin Chen, Xiaoyan Hu, Yichao Cai, Jie Lin, Bangyan Wang, Jiesen Li, Youqin Chen, Jun Peng

Pages: 5959-5967 Published online on: 11 October 2019
Open Access

Silencing of KCNK15‑AS1 inhibits lung cancer cell proliferation via upregulation of miR‑202 and miR‑370

Jun Peng, Xin‑Long Chen, Hong‑Zhong Cheng, Zhe‑Yuan Xu, Han Wang, Zhi‑Zhou Shi, Jun Liu, Xian‑Gu Ning, Hao Peng

Pages: 5968-5976 Published online on: 02 October 2019
Open Access

A subset of patients with MSS/MSI‑low‑colorectal cancer showed increased CD8(+) TILs together with up‑regulated IFN‑γ

Tomohiro Kikuchi, Kosaku Mimura, Hirokazu Okayama, Yuko Nakayama, Katsuharu Saito, Leo Yamada, Eisei Endo, Wataru Sakamoto, Shotaro Fujita, Hisahito Endo, Motonobu Saito, Tomoyuki Momma, Zenichiro Saze, Shinji Ohki, Koji Kono

Pages: 5977-5985 Published online on: 02 October 2019
Open Access

MicroRNA‑33a‑5p overexpression sensitizes triple‑negative breast cancer to doxorubicin by inhibiting eIF5A2 and epithelial‑mesenchymal transition

Xiaoqing Guan, Shucheng Gu, Mu Yuan, Xiangxin Zheng, Ji Wu

Pages: 5986-5994 Published online on: 14 October 2019
Open Access

The core genes involved in the promotion of depression in patients with ovarian cancer

Yuexiong Yi, Yanyan Liu, Kejia Wu, Wanrong Wu, Wei Zhang

Pages: 5995-6007 Published online on: 30 September 2019
Open Access

Bioinformatics analysis of Ewing's sarcoma: Seeking key candidate genes and pathways

Jinming Zhang, Yao Zhang, Ze Li, Hongzeng Wu, Jianjun Xun, Helin Feng

Pages: 6008-6016 Published online on: 30 September 2019
Open Access

Bioinformatics analysis of potential therapeutic targets among ARHGAP genes in breast cancer

Wei‑Xian Chen, Ming Lou, Lin Cheng, Qi Qian, Ling‑Yun Xu, Li Sun, Yu‑Lan Zhu, Hong Dai

Pages: 6017-6025 Published online on: 02 October 2019
Open Access

Cytochrome C inhibits tumor growth and predicts favorable prognosis in clear cell renal cell carcinoma

Zhiguo Liu, Xiancheng Zhao, Liang Zhang, Bing Pei

Pages: 6026-6032 Published online on: 14 October 2019
Open Access

Identification of core differentially methylated genes in glioma

Jing Xue, Hai‑Xia Gao, Wei Sang, Wen‑Li Cui, Ming Liu, Yan Zhao, Meng‑Bo Wang, Qian Wang, Wei Zhang

Pages: 6033-6045 Published online on: 02 October 2019
Open Access

Cyclin‑dependent kinase 9 expression and its association with CD8+ T cell infiltration in microsatellite‑stable colorectal cancer

Jiefu Wang, Jia Liu, Fei Tian, Yang Zhan, Dalu Kong

Pages: 6046-6056 Published online on: 08 October 2019
Open Access

PLCB4 upregulation is associated with unfavorable prognosis in pediatric acute myeloid leukemia

Shiwen Wu, Wei Zhang, Dongqin Shen, Jianle Lu, Li Zhao

Pages: 6057-6065 Published online on: 25 September 2019
Open Access

Prognostic genes of melanoma identified by weighted gene co‑expression network analysis and drug repositioning using a network‑based method

Lu Wang, Chuan‑Yuan Wei, Yuan‑Yuan Xu, Xin‑Yi Deng, Qiang Wang, Jiang‑Hui Ying, Si‑Min Zhang, Xin Yuan, Tian‑Fan Xuan, Yu‑Yan Pan, Jian‑Ying Gu

Pages: 6066-6078 Published online on: 04 October 2019
Open Access

Identification of biomarkers and construction of a microRNA‑mRNA regulatory network for ependymoma using integrated bioinformatics analysis

Biao Yang, Jun‑Xi Dai, Yuan‑Bo Pan, Yan‑Bin Ma, Sheng‑Hua Chu

Pages: 6079-6089 Published online on: 30 September 2019
Open Access

Deep learning techniques for detecting preneoplastic and neoplastic lesions in human colorectal histological images

Paola Sena, Rita Fioresi, Francesco Faglioni, Lorena Losi, Giovanni Faglioni, Luca Roncucci

Pages: 6101-6107 Published online on: 27 September 2019
Open Access

Mutant‑allele tumor heterogeneity in malignant glioma effectively predicts neoplastic recurrence

Pengfei Wu, Wei Yang, Jianxing Ma, Jingyu Zhang, Maojun Liao, Lunshan Xu, Minhui Xu, Liang Yi

Pages: 6108-6116 Published online on: 11 October 2019
Open Access

Shikonin regulates invasion and autophagy of cultured colon cancer cells by inhibiting yes‑associated protein

Jing Zhu, Lei Zhao, Bin Luo, Wang Sheng

Pages: 6117-6125 Published online on: 11 October 2019
Open Access

Prognostic value and prospective molecular mechanism of miR‑100‑5p in hepatocellular carcinoma: A comprehensive study based on 1,258 samples

Qing‑Lin He, Shan‑Yu Qin, Lin Tao, Hong‑Jian Ning, Hai‑Xing Jiang

Pages: 6126-6142 Published online on: 04 October 2019
Open Access

Metabolic tumor volume predicts overall survival in patients with primary pulmonary lymphoepithelioma‑like carcinoma

Chun‑Yu Lin, Yu‑Chuan Chang, I‑Ting Wang, Meng‑Heng Hsieh, Chih‑Wei Wang, Shu‑Min Lin, Ching‑Yang Wu, Yueh‑Fu Fang

Pages: 6143-6149 Published online on: 02 October 2019
Open Access

Identification of differentially expressed microRNAs and the potential of microRNA‑455‑3p as a novel prognostic biomarker in glioma

Wei Wang, Shuwen Mu, Qingshuang Zhao, Liang Xue, Shousen Wang

Pages: 6150-6156 Published online on: 27 September 2019
Open Access

Ewing's sarcoma in the spinal canal of T12‑L3: A case report and review of the literature

Dajun Yan, Jie Zhang, Dequan Zhong

Pages: 6157-6163 Published online on: 03 October 2019
Open Access

A three long non‑coding RNA signature to improve survival prediction in patients with Wilms' tumor

Ping Ren, Meiling Hu

Pages: 6164-6170 Published online on: 14 October 2019
Open Access

High gene expression levels of VEGFA and CXCL8 in the peritumoral brain zone are associated with the recurrence of glioblastoma: A bioinformatics analysis

Xiaobin Luo, Shangyi Xu, Yali Zhong, Tianqi Tu, Youlin Xu, Xianglong Li, Bin Wang, Fubing Yang

Pages: 6171-6179 Published online on: 14 October 2019
Open Access

Value of ultrasound combined with MRI in the diagnosis of primary and recurrent hepatocellular carcinoma

Xiaoli Ji, Shisheng Zhou, Peng Yang, Faqin Liu, Yan Li, Hong Li

Pages: 6180-6186 Published online on: 02 October 2019
Open Access

Predictive values of miR‑129 and miR‑139 for efficacy on patients with prostate cancer after chemotherapy and prognostic correlation

Zhongchun Hu, Junjie Guo, Ming Zhao, Tao Jiang, Xiaofeng Yang

Pages: 6187-6195 Published online on: 02 October 2019

Hepatitis B virus infection and 1q21 amplification in multiple myeloma

Dan Guo, Peipei Xu, Chaoyang Guan, Yong Xu, Yonggong Yang, Jingyan Xu, Rongfu Zhou, Bing Chen

Pages: 6196-6206 Published online on: 27 September 2019

Novel sphingomyelin biomarkers for brain glioma and associated regulation research on the PI3K/Akt signaling pathway

Xiao‑Hui Zhai, Jian Xiao, Jie‑Kai Yu, Hong Sun, Shu Zheng

Pages: 6207-6213 Published online on: 02 October 2019

Decreased expression levels of ELOVL6 indicate poor prognosis in hepatocellular carcinoma

Hui Li, Xianling Wang, Jun Tang, Haibo Zhao, Min Duan

Pages: 6214-6220 Published online on: 09 October 2019

Molecular mechanism of Helicobacter pylori‑induced autophagy in gastric cancer (Review)

Fan Zhang, Cong Chen, Jike Hu, Ruiliang Su, Junqiang Zhang, Zhijian Han, Hao Chen, Yumin Li

Pages: 6221-6227 Published online on: 10 October 2019

Mitotically‑associated long non‑coding RNA promotes cancer cell proliferation in hepatocellular carcinoma by downregulating miR‑122a

Xuejing Zhang, Hongling Li, Mingfeng Mao, Xiangyang Wang, Jingjing Zheng, Shunshi Yang

Pages: 6237-6242 Published online on: 02 October 2019

Growth inhibitory effects of PC‑NSAIDs on human breast cancer subtypes in cell culture

Shelley Burge, Lenard M. Lichtenberger

Pages: 6243-6248 Published online on: 02 October 2019

In vitro antitumor effects of FGFR and PI3K inhibitors on human papillomavirus positive and negative tonsillar and base of tongue cancer cell lines

Stefan Holzhauser, Ourania N. Kostopoulou, Anna Ohmayer, Birthe K.A. Lange, Torbjörn Ramqvist, Teodora Andonova, Cinzia Bersani, Malin Wickström, Tina Dalianis

Pages: 6249-6260 Published online on: 09 October 2019

Silencing long intergenic non‑coding RNA 00707 enhances cisplatin sensitivity in cisplatin‑resistant non‑small‑cell lung cancer cells by sponging miR‑145

Hongde Zhang, Yi Luo, Wenli Xu, Kang Li, Changzheng Liao

Pages: 6261-6268 Published online on: 03 October 2019

Hypoxia induces immunogenic cell death of cancer cells by enhancing the exposure of cell surface calreticulin in an endoplasmic reticulum stress‑dependent manner

Yu Kyeong Han, Ga‑Young Park, Min Ji Bae, Joong Sun Kim, Wol Soon Jo, Chang Geun Lee

Pages: 6269-6274 Published online on: 14 October 2019

Novel serum markers HSP60, CHI3L1, and IGFBP-2 in metastatic colorectal cancer

Michal Vocka, Daniel Langer, Vladimir Fryba, Jaromir Petrtyl, Tomas Hanus, Marta Kalousova, Tomas Zima, Lubos Petruzelka

Pages: 6284-6292 Published online on: 26 September 2019

MicroRNAs associated with microvascular invasion in hepatocellular carcinoma and their prognostic impacts in patients undergoing hepatic resection

Sung Kyu Song, Min Geun Park, Seung‑Keun Park, Chul‑Woon Chung, Yongkeun Park

Pages: 6293-6303 Published online on: 14 October 2019
Open Access

[Corrigendum] A germline alteration of ERBB2 increases the risk of breast cancer in Chinese Han women with a familial history of malignant tumors

Yan Ju, Lifeng Wang, Shengjun Ta, Rui Shu, Shanling Yang, Xican Gao, Hongping Song, Liwen Liu

Pages: 6304-6304 Published online on: 27 September 2019
Open Access

[Retracted] Breast metastasis from a pulmonary adenocarcinoma: Case report and review of the literature

Alessandro Sanguinetti, Francesco Puma, Roberta Lucchini, Stefano Santoprete, Roberto Cirocchi, Alessia Corsi, Roberta Triola, Nicola Avenia

Pages: 6305-6305 Published online on: 04 October 2019
Open Access

Long non‑coding RNA RNCR3 promotes glioma progression involving the Akt/GSK‑3β pathway

Bing Zhu, Shenyan Zhang, Ning Meng, He Zhang, Shaoji Yuan, Jin Zhang

Pages: 6315-6322 Published online on: 18 October 2019
Open Access

Association of high PDPN expression with pulmonary metastasis of osteosarcoma and patient prognosis

Xincheng Wang, Wei Li, Jiaqi Bi, Jia Wang, Linying Ni, Qingtao Shi, Qinggang Meng

Pages: 6323-6330 Published online on: 05 November 2019
Open Access

Long non‑coding RNA zinc finger antisense 1 functions as an oncogene in acute promyelocytic leukemia cells

Lifang Su, Hongwei Kong, Fenzhi Wu, Hongjiao Lv, Wenping Wu, Gang Wang, Xuefen Yan, Jiaheng Wang, Qiang Fang

Pages: 6331-6338 Published online on: 29 October 2019
Open Access

miR‑203a‑3p.1 is involved in the regulation of osteogenic differentiation by directly targeting Smad9 in MM‑MSCs

Fang‑Yi Fan, Rui Deng, Ling Qiu, Qin Wen, Yunjing Zeng, Li Gao, Chen Zhang, Peiyan Kong, Jiangfan Zhong, Ningyu Zeng, Zhengyu Li, Yi Su, Xi Zhang

Pages: 6339-6346 Published online on: 17 October 2019
Open Access

Tissue factor expression predicts outcome in children with neuroblastoma: A retrospective study

Laila M. Sherief, Tamer H. Hassan, Marwa Zakaria, Manar Fathy, Elia A. Eshak, Marwa A. Bebars, Asmaa Esh

Pages: 6347-6354 Published online on: 30 October 2019
Open Access

Granular cell tumors overexpress TFE3 without gene rearrangement: Evaluation of immunohistochemistry and break‑apart FISH in 45 cases

Yang Liu, Qin Zheng, Chen Wang, Jinping Wang, Jian Ming, Yong Zhang, Xiaoman Li, William Chi‑Shing Cho, Liang Wang, Qing‑Chang Li, Xue‑Shan Qiu, En‑Hua Wang

Pages: 6355-6360 Published online on: 17 October 2019
Open Access

Colorectal cancer cells differentially impact migration and microRNA expression in endothelial cells

Do Yei Kim, Sang‑Soo Lee, Young‑Kyung Bae

Pages: 6361-6370 Published online on: 05 November 2019
Open Access

Integrated analysis of lncRNA CTD‑2357A8.3 expression and its potential roles in head and neck squamous cell carcinoma

Bo Zou, Xin Guan, Wen Zhang, Dong Wang, Kai Xu, Dao‑Ying Yuan, Zhen Meng, Bin Zhang

Pages: 6371-6378 Published online on: 25 September 2019
Open Access

Altered expression of lncRNA NCK1‑AS1 distinguished patients with prostate cancer from those with benign prostatic hyperplasia

Zhihui Guan, Yuwei Song, Jinguo Ma, Feng Li, Xiaojun Zhao, Guodong Liang, Haiquan An, Jinxian Pu

Pages: 6379-6384 Published online on: 01 November 2019
Open Access

The inhibitory effects of cisplatin‑radiation combination treatment on malignant osteosarcoma MG‑63 cells and BRCA1‑p53 pathways are more efficient than single treatments

Hong‑Bin Sun, He‑Yuan Wang, Bing Wu, Zhong‑Feng Wang, Li‑Zhe Wang, Fu‑Qiang Li, Jun‑Duo Wu, Le‑Ning Zhang

Pages: 6385-6396 Published online on: 29 October 2019
Open Access

Detection of circulating colorectal cancer cells by a custom microfluid system before and after endoscopic metallic stent placement

Rei Ishibashi, Shuntaro Yoshida, Nariaki Odawara, Takahiro Kishikawa, Ryo Kondo, Ayako Nakada, Ryunosuke Hakuta, Naminatsu Takahara, Eri Tanaka, Kazuma Sekiba, Takahiro Seimiya, Takashi Ohnaga, Motoyuki Otsuka, Kazuhiko Koike

Pages: 6397-6404 Published online on: 04 November 2019
Open Access

FORCE dual‑energy CT in pathological grading of clear cell renal cell carcinoma

Chunling Zhang, Ning Wang, Xinyou Su, Kun Li, Dexin Yu, Aimei Ouyang

Pages: 6405-6412 Published online on: 30 October 2019
Open Access

Radioimmunoimaging of 125I‑labeled anti‑CD93 monoclonal antibodies in a xenograft model of non‑small cell lung cancer

Weiwei Liu, Chao Zhang, Hui Cao, Dai Shi, Shanshan Zhao, Ting Liang, Guihua Hou

Pages: 6413-6422 Published online on: 01 November 2019
Open Access

Retrospective analysis of transcatheter arterial chemoembolization treatment for spontaneously ruptured hepatocellular carcinoma

Jixue Zou, Chao Li, Yi Chen, Rongxin Chen, Tongchun Xue, Xiaoying Xie, Lan Zhang, Zhenggang Ren

Pages: 6423-6430 Published online on: 01 November 2019
Open Access

Slow skeletal muscle troponin T, titin and myosin light chain 3 are candidate prognostic biomarkers for Ewing's sarcoma

Yajun Deng, Qiqi Xie, Guangzhi Zhang, Shaoping Li, Zuolong Wu, Zhanjun Ma, Xuegang He, Yicheng Gao, Yonggang Wang, Xuewen Kang, Jing Wang

Pages: 6431-6442 Published online on: 04 November 2019
Open Access

Clinicopathological and molecular characteristics of abdominal desmoid tumors in the Chinese population: A single‑center report of 15 cases

Jiongyuan Wang, Ning Jia, Qiaowei Lin, Yuan Huang, Jinglei Li, Quan Jiang, Wenshuai Liu, Jing Xu, Yingyong Hou, Ju Liu, Ming Li, Weiqi Lu, Yuhong Zhou, Yong Zhang, Hanxing Tong

Pages: 6443-6450 Published online on: 01 November 2019
Open Access

Epidermal growth factor receptor mutation subtype has differential effects on adjuvant chemotherapy for resected adenocarcinoma pathological stages II‑III

Yohei Kawaguchi, Tetsuya Okano, Kentaro Imai, Sachio Maehara, Junichi Maeda, Koichi Yoshida, Masaru Hagiwara, Masatoshi Kakihana, Naohiro Kajiwara, Tatsuo Ohira, Jun Matsubayashi, Norihiko Ikeda

Pages: 6451-6458 Published online on: 04 November 2019
Open Access

High hnRNP AB expression is associated with poor prognosis in patients with colorectal cancer

Jun‑Min Zhou, Hang Jiang, Tao Yuan, Guang‑Xun Zhou, Xiang‑Bing Li, Kun‑Ming Wen

Pages: 6459-6468 Published online on: 01 November 2019
Open Access

Efficacy of regorafenib in acute pulmonary carcinomatous lymphangitis as a manifestation of rectal cancer: A case report

Nobumichi Takeuchi, Kumiko Koike, Sonomi Yoshida, Masayuki Fujiwara

Pages: 6469-6474 Published online on: 04 November 2019
Open Access

Tauroursodeoxycholic acid mediates endoplasmic reticulum stress and autophagy in adrenocortical carcinoma cells

Xuemei Huang, Lili Wu, Yaqi Kuang, Xin Li, Xiujun Deng, Xinghuan Liang, Li Li, Haiyan Yang, Zhenxing Huang, Decheng Lu, Zuojie Luo

Pages: 6475-6482 Published online on: 05 November 2019
Open Access

Elevated MIR100HG promotes colorectal cancer metastasis and is associated with poor prognosis

Wenhua Li, Fukang Yuan, Xin Zhang, Wanyuan Chen, Xuejun Tang, Lungen Lu

Pages: 6483-6490 Published online on: 05 November 2019
Open Access

miR‑221‑3p and miR‑15b‑5p promote cell proliferation and invasion by targeting Axin2 in liver cancer

Yefeng Dong, Nannan Zhang, Suming Zhao, Xiaoyang Chen, Feng Li, Xia Tao

Pages: 6491-6500 Published online on: 05 November 2019
Open Access

miR‑331‑3p suppresses cell invasion and migration in colorectal carcinoma by directly targeting NRP2

Hongye Zhang, Ruiyu Wang, Mingxia Wang

Pages: 6501-6508 Published online on: 01 November 2019
Open Access

Receptor tyrosine kinase expression in high‑grade gliomas before and after chemoradiotherapy

Kuanyu Wang, Ruoyu Huang, Chenxing Wu, Guanzhang Li, Zheng Zhao, Huimin Hu, Yanwei Liu

Pages: 6509-6515 Published online on: 29 October 2019
Open Access

Identification of hub genes and key pathways associated with the progression of gynecological cancer

Xi Zhang, Yudong Wang

Pages: 6516-6524 Published online on: 18 October 2019
Open Access

Cytokine‑induced killer cells/natural killer cells combined with anti‑GD2 monoclonal antibody increase cell death rate in neuroblastoma SK‑N‑SH cells

Chi Zhang, Xilin Xiong, Yang Li, Ke Huang, Ling Liu, Xiaomin Peng, Wenjun Weng

Pages: 6525-6535 Published online on: 29 October 2019
Open Access

Inhibition of microRNA‑221‑5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells

Fang‑Yi Fan, Rui Deng, Si‑Han Lai, Qin Wen, Yunjing Zeng, Lei Gao, Yao Liu, Peiyan Kong, Jiangfan Zhong, Yi Su, Xi Zhang

Pages: 6536-6544 Published online on: 17 October 2019
Open Access

Prognostic phenotypic classification for canine mammary tumors

Giovanna Rossi Varallo, Gabriela Bottaro Gelaleti, Larissa Bazela Maschio‑Signorini, Marina Gobbe Moschetta, Juliana Ramos Lopes, Andrigo Barboza De Nardi, Mirela Tinucci‑Costa, Rafael Malagoli Rocha, Debora Aparecida Pires de Campos Zuccari

Pages: 6545-6553 Published online on: 05 November 2019
Open Access

Tanshinone IIA reverses EGF‑ and TGF‑β1‑mediated epithelial‑mesenchymal transition in HepG2 cells via the PI3K/Akt/ERK signaling pathway

Longkai Zhang, Weibin Lin, Xiaodan Chen, Gang Wei, Hailong Zhu, Shangping Xing

Pages: 6554-6562 Published online on: 01 November 2019
Open Access

Correlation between cytotoxicity in cancer cells and free radical‑scavenging activity: In vitro evaluation of 57 medicinal and edible plant extracts

Marei Sammar, Basheer Abu‑Farich, Ibrahim Rayan, Mizied Falah, Anwar Rayan

Pages: 6563-6571 Published online on: 05 November 2019
Open Access

Differences in the early stage gene expression profiles of lung adenocarcinoma and lung squamous cell carcinoma

Nitin Venugopal, Justin Yeh, Sai Karthik Kodeboyina, Tae Jin Lee, Shruti Sharma, Nikhil Patel, Ashok Sharma

Pages: 6572-6582 Published online on: 21 October 2019
Open Access

Identification of key candidate genes for colorectal cancer by bioinformatics analysis

Zhihua Chen, Yilin Lin, Ji Gao, Suyong Lin, Yan Zheng, Yisu Liu, Shao Qin Chen

Pages: 6583-6593 Published online on: 17 October 2019
Open Access

Survival of patients with resected primary colorectal mucinous adenocarcinoma: A competing risk nomogram analysis

Dongjun Dai, Bingluo Zhou, Yiming Zhong, Hongchuan Jin, Xian Wang

Pages: 6594-6604 Published online on: 30 October 2019
Open Access

A novel prognostic nomogram based on 5 long non‑coding RNAs in clear cell renal cell carcinoma

Sheng Wang, Kequn Chai, Jiabin Chen

Pages: 6605-6613 Published online on: 18 October 2019
Open Access

Myricetin inhibits migration and invasion of hepatocellular carcinoma MHCC97H cell line by inhibiting the EMT process

Hongxin Ma, Lei Zhu, Jingna Ren, Benlong Rao, Maomao Sha, Yi Kuang, Weigan Shen, Zhengxin Xu

Pages: 6614-6620 Published online on: 18 October 2019
Open Access

Prognostic and clinicopathological value of ZIC1 in patients with cervical squamous cell carcinoma

Xing Gu, Xue‑Ke Guo, Bi‑Hui Chen, Xiao‑Jiao Gao, Fang Chen, Qin Liu

Pages: 6621-6627 Published online on: 18 October 2019
Open Access

Differentiation and roles of bone marrow‑derived cells on the tumor microenvironment of oral squamous cell carcinoma

Chang Anqi, Kiyofumi Takabatake, Hotaka Kawai, May Wathone Oo, Saori Yoshida, Masae Fujii, Haruka Omori, Shintaro Sukegawa, Keisuke Nakano, Hidetsugu Tsujigiwa, Zheng Jinhua, Hitoshi Nagatsuka

Pages: 6628-6638 Published online on: 04 November 2019
Open Access

Development of new software enabling automatic identification of the optimal anatomical liver resectable region, incorporating preoperative liver function

Mitsugi Shimoda, Masanori Hariyama, Yukio Oshiro, Shuji Suzuki

Pages: 6639-6647 Published online on: 18 October 2019
Open Access

Expression and role of HEPIS in breast cancer

Fen Hu, Yunfeng Zhang, Mi Li, Yun Bai, Xiujun Zhang

Pages: 6648-6656 Published online on: 17 October 2019
Open Access

Expression levels and prognostic values of annexins in liver cancer

Chunbo Zhuang, Pei Wang, Ting Sun, Lei Zheng, Liang Ming

Pages: 6657-6669 Published online on: 30 October 2019
Open Access

Identification of potential pathogenic candidates or diagnostic biomarkers in papillary thyroid carcinoma using expression and methylation profiles

Songfeng Wei, Xinwei Yun, Xianhui Ruan, Xi Wei, Xiangqian Zheng, Ming Gao

Pages: 6670-6678 Published online on: 05 November 2019
Open Access

Identification of key candidate genes and pathways in endometrial cancer: Evidence from bioinformatics analysis

Sha Lv, Xiaoxiao Xu, Zhangying Wu

Pages: 6679-6689 Published online on: 01 November 2019
Open Access

Prognosis and endocrine therapy selection for patients with low hormone receptor‑positive breast cancer following neoadjuvant chemotherapy: A retrospective study of 570 patients in China

Yuqin Ding, Kaijing Ding, Kun Yu, Dehong Zou, Hongjian Yang, Xiangming He, Wenju Mo, Xingfei Yu, Xiaowen Ding

Pages: 6690-6696 Published online on: 01 November 2019
Open Access

Upregulation of Holliday junction recognition protein predicts poor prognosis and biochemical recurrence in patients with prostate cancer

Yan‑Fei Chen, Yu‑Xiang Liang, Jian‑An Yang, Dao‑Zhang Yuan, Jing Li, Shun‑Sheng Zheng, Yue‑Ping Wan, Bin Wang, Zhao‑Dong Han, Wei‑De Zhong

Pages: 6697-6703 Published online on: 05 November 2019
Open Access

An extra chromosome 9 derived from either a normal chromosome 9 or a derivative chromosome 9 in a patient with acute myeloid leukemia positive for t(9;11)(p21.3;q23.3): A case report

Man Gao, Hui Pang, Young Mi Kim, Xianglan Lu, Xianfu Wang, Jiyun Lee, Mingwei Wang, Fanzheng Meng, Shibo Li

Pages: 6725-6731 Published online on: 01 November 2019
Open Access

PTEN‑knockdown disrupts the morphology, growth pattern and function of Nthy‑Ori 3‑1 cells by downregulating PAX8 expression

Zhuo Sun, Jinqi Lu, Muyu Wu, Changli Ouyang, Yueping Xing, Xiancun Hou, Zhenduo Shi, Yongping Wu

Pages: 6732-6740 Published online on: 31 October 2019
Open Access

Identification of potential hub genes associated with the pathogenesis and prognosis of pancreatic duct adenocarcinoma using bioinformatics meta‑analysis of multi‑platform datasets

Yufan Ma, Yinquan Pu, Li Peng, Xujuan Luo, Jin Xu, Yan Peng, Xiaowei Tang

Pages: 6741-6751 Published online on: 04 November 2019
Open Access

YAP promotes gastric cancer cell survival and migration/invasion via the ERK/endoplasmic reticulum stress pathway

Haibin Liu, Dong Mei, Pengcheng Xu, Haisheng Wang, Yan Wang

Pages: 6752-6758 Published online on: 04 November 2019
Open Access

MicroRNA‑133a inhibits the proliferation of non‑small cell lung cancer by targeting YES1

Yuyao Shen, Fangwei Chen, Yanchao Liang

Pages: 6759-6765 Published online on: 01 November 2019
Open Access

Prognosis and outcome of patients with acute myeloid leukemia based on FLT3‑ITD mutation with or without additional abnormal cytogenetics

Shandong Tao, Chunling Wang, Yue Chen, Yuan Deng, Lixiao Song, Yuyue Shi, Lanlan Ling, Banghe Ding, Zhengmei He, Liang Yu

Pages: 6766-6774 Published online on: 05 November 2019

LncRNA AWPPH promotes the invasion and migration of glioma cells through the upregulation of HIF1α

Ting Zhang, Fei Wang, Yuzhi Liao, Lei Yuan, Baozhong Zhang

Pages: 6781-6786 Published online on: 29 October 2019

Long noncoding RNA IRAIN acts as tumor suppressor via miR‑125b in multiple myeloma

Yanxia Jiang, Jian Chen, Guoan Chen

Pages: 6787-6794 Published online on: 21 October 2019

lncRNA PCAT19 negatively regulates p53 in non‑small cell lung cancer

Xiaokai Zhang, Qiwen Wang, Yajuan Xu, Bao Wang, Chunyi Jia, Lei Wang, Hongmei Sun, Hui Zhao, Zhe Wang, Qinguang Zou, Shaolin Sun, Lixin Zhang

Pages: 6795-6800 Published online on: 04 November 2019

Upregulation of MANCR predicts poor survival in patients with gastric cancer

Ling Yao, Jinhua Yan, Lihong Gan, Shenan Huang, Fei Cheng, Nian Fang

Pages: 6801-6806 Published online on: 30 October 2019

p53 protein expression affected by TP53 polymorphism is associated with the biological behavior and prognosis of low rectal cancer

Guangzhe Zhang, Qian Xu, Zeyang Wang, Liping Sun, Zhi Lv, Jingwei Liu, Chengzhong Xing, Yuan Yuan

Pages: 6807-6821 Published online on: 18 October 2019

miR‑125b suppresses cellular proliferation by targeting c‑FLIP in gallbladder carcinoma

Huajie Zong, Huading Zhou, Yang Xiang, Gang Wu

Pages: 6822-6828 Published online on: 18 October 2019
Open Access

Sufentanil impairs autophagic degradation and inhibits cell migration in NCI‑H460 in vitro

Hui Jiang, Hongxian Wang, Weiwei Zou, Yuexia Hu, Chen Chen, Chunhui Wang

Pages: 6829-6835 Published online on: 17 October 2019

hsa_circRNA_100873 upregulation is associated with increased lymphatic metastasis of esophageal squamous cell carcinoma

Bin Zheng, Zhigang Wu, Songtao Xue, Hao Chen, Shuliang Zhang, Taidui Zeng, Guobing Xu, Weidong Wu, Wei Zheng, Chun Chen

Pages: 6836-6844 Published online on: 18 October 2019

Combination of contrast‑enhanced ultrasound and strain elastography to assess cytologically non‑diagnostic thyroid nodules

Zi‑Mei Lin, Qing Wen, Cao‑Xin Yan, Min‑Qiang Pan, Guo‑Qiang Mo, Ji‑Fan Chen, Pin‑Tong Huang

Pages: 6845-6851 Published online on: 05 November 2019

Sex‑biased differences in the correlation between epithelial‑to‑mesenchymal transition‑associated genes in cancer cell lines

Sun Young Kim, Seungeun Lee, Eunhye Lee, Hyesol Lim, Ji Yoon Shin, Joohee Jung, Sang Geon Kim, Aree Moon

Pages: 6852-6868 Published online on: 29 October 2019

The modulation study of multiple drug resistance in bladder cancer by curcumin and resveratrol

Chun‑Jung Cho, Ching‑Wei Yang, Chia‑Lun Wu, Jar‑Yi Ho, Cheng‑Ping Yu, Sheng‑Tang Wu, Dah‑Shyong Yu

Pages: 6869-6876 Published online on: 30 October 2019

Association between breast cancer cell migration and radiosensitivity in vitro

Jing Hou, Leilei Li, Haizhen Zhu, Huan Chen, Na Wei, Min Dai, Qing Ni, Xiaomao Guo

Pages: 6877-6884 Published online on: 31 October 2019

Peripheral primitive neuroectodermal tumors: A retrospective analysis of 89 cases and literature review (Review)

Liming Gao, Yingying Zhu, Xiaohua Shi, Zhiqiang Gao, Xingming Chen

Pages: 6885-6890 Published online on: 18 October 2019

Methylselenol producing selenocompounds enhance the efficiency of mammaglobin‑A peptide vaccination against breast cancer cells

Duaa Babaer, Mu Zheng, Michael T. Ivy, Roy Zent, Venkataswarup Tiriveedhi

Pages: 6891-6898 Published online on: 18 October 2019
Open Access

SPINK1 is a prognosis predicting factor of non‑small cell lung cancer and regulates redox homeostasis

Maoqing Guo, Xuan Zhou, Xiao Han, Youwen Zhang, Luning Jiang

Pages: 6899-6908 Published online on: 18 October 2019

A combination of inhibitors of glycolysis, glutaminolysis and de novo fatty acid synthesis decrease the expression of chemokines in human colon cancer cells

Alejandro Schcolnik‑Cabrera, Guadalupe Dominguez‑Gómez, Alma Chávez‑Blanco, Marisol Ramírez‑Yautentzi, Rocío Morales‑Bárcenas, José Chávez‑Díaz, Lucía Taja‑Chayeb, Alfonso Dueñas‑González

Pages: 6909-6916 Published online on: 18 October 2019

6‑gene promoter methylation assay is potentially applicable for prostate cancer clinical staging based on urine collection following prostatic massage

Kostyantyn A. Nekrasov, Mark V. Vikarchuk, Evgeniya E. Rudenko, Igor V. Ivanitskiy, Viacheslav M. Grygorenko, Rostyslav O. Danylets, Alexander G. Kondratov, Liubov A. Stoliar, Bizhan R. Sharopov, Volodymyr I. Kashuba

Pages: 6917-6925 Published online on: 29 October 2019

Gene expression of ASNS, LGMN and CTSB is elevated in a subgroup of childhood BCP‑ALL with PAX5 deletion

Ewa Wrona, Justyna Jakubowska, Bartłomiej Pawlik, Agata Pastorczak, Joanna Madzio, Monika Lejman, Łukasz Sędek, Jerzy Kowalczyk, Tomasz Szczepański, Wojciech Młynarski

Pages: 6926-6932 Published online on: 04 November 2019
Open Access

[Corrigendum] microRNA‑34a overexpression inhibits cell migration and invasion via regulating SIRT1 in hepatocellular carcinoma

Jianhui Zhou, Wenying Zhou, Fangen Kong, Xiaoyu Xiao, Haoyu Kuang, Yingxian Zhu

Pages: 6933-6934 Published online on: 04 November 2019
Journal Cover

December 2019
Volume 18 Issue 6

Print ISSN: 1792-1074
Online ISSN: 1792-1082

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