Journal Articles

Open Access

Apoptosis induced by bruceine D in human non‑small‑cell lung cancer cells involves mitochondrial ROS‑mediated death signaling

Jian‑Hui Xie, Zheng‑Quan Lai, Xing‑Han Zheng, Yan‑Fang Xian, Qian Li, Siu‑Po Ip, You‑Liang Xie, Jian‑Nan Chen, Zi‑Ren Su, Zhi‑Xiu Lin, Xiao‑Bo Yang

Pages: 2015-2026 Published online on: 03 October 2019
Open Access

Screening for differentially‑expressed microRNA biomarkers in Saudi colorectal cancer patients by small RNA deep sequencing

Yazeed A. Al‑Sheikh, Hazem K. Ghneim, Khalid K. Alharbi, Mourad A.M. Aboul‑Soud

Pages: 2027-2036 Published online on: 02 October 2019
Open Access

Stop codons and the +4 nucleotide may influence the efficiency of G418 in rescuing nonsense mutations of the HERG gene

Haiyun Yu, Yanhai Meng, Shuhong Zhang, Chen Tian, Fang Wu, Ning Li, Qiuyang Li, Yulan Jin, Jielin Pu

Pages: 2037-2046 Published online on: 01 October 2019
Open Access

FSH1 regulates the phenotype and pathogenicity of the pathogenic dermatophyte Microsporum canis

Furong Zhang, Can Tan, Yu Xu, Guoling Yang

Pages: 2047-2056 Published online on: 27 September 2019
Open Access

The goat β‑casein/CMV chimeric promoter drives the expression of hLF in transgenic goats produced by cell transgene microinjection

Ting Zhang, Yuguo Yuan, Rui Lu, Sheng Xu, Minya Zhou, Tingting Yuan, Yaoyao Lu, Kunning Yan, Yong Cheng

Pages: 2057-2064 Published online on: 24 October 2019
Open Access

Redd1 protects against post‑infarction cardiac dysfunction by targeting apoptosis and autophagy

Pianpian Huang, Jun Fu, Long Chen, Chenhui Ju, Kefei Wu, Hongxia Liu, Yun Liu, Benming Qi, Benling Qi, Lihua Liu

Pages: 2065-2076 Published online on: 04 October 2019
Open Access

Upregulation of sphingosine kinase 1 contributes to ventilator-associated lung injury in a two-hit model

Yan Wang, Ting‑Ting Gao, Dun‑Feng Xu, Xiao‑Yan Zhu, Wen‑Wen Dong, Zhou Lv, Yu‑Jian Liu, Lai Jiang

Pages: 2077-2090 Published online on: 21 October 2019
Open Access

Protective effect of hydrogen sulfide on monocrotaline‑induced pulmonary arterial hypertension via inhibition of the endothelial mesenchymal transition

Hui Zhang, Yanjun Lin, Yiwen Ma, Junfeng Zhang, Changqian Wang, Huili Zhang

Pages: 2091-2102 Published online on: 01 October 2019
Open Access

Adipose‑derived stem cells overexpressing SK4 calcium‑activated potassium channel generate biological pacemakers

Mei Yang, Qingyan Zhao, Hongyi Zhao, Ankang Yang, Fengyuan Wang, Xi Wang, Yanhong Tang, Congxin Huang

Pages: 2103-2112 Published online on: 16 October 2019
Open Access

TPX2 silencing exerts anti‑tumor effects on hepatocellular carcinoma by regulating the PI3K/AKT signaling pathway

Dan‑Hong Huang, Jie Jian, Shuang Li, Yan Zhang, Li‑Zhen Liu

Pages: 2113-2122 Published online on: 14 October 2019
Open Access

Roles of p38α and p38β mitogen‑activated protein kinase isoforms in human malignant melanoma A375 cells

Su‑Ying Wen, Shi‑Yann Cheng, Shang‑Chuan Ng, Ritu Aneja, Chih‑Jung Chen, Chih‑Yang Huang, Wei‑Wen Kuo

Pages: 2123-2132 Published online on: 24 October 2019
Open Access

Feasibility of tumor‑derived exosome enrichment in the onco‑hematology leukemic model of chronic myeloid leukemia

Simona Bernardi, Chiara Foroni, Camilla Zanaglio, Federica Re, Nicola Polverelli, Alessandro Turra, Enrico Morello, Mirko Farina, Federica Cattina, Lisa Gandolfi, Tatiana Zollner, Eugenia Accorsi Buttini, Michele Malagola, Domenico Russo

Pages: 2133-2144 Published online on: 14 October 2019
Open Access

lncRNA/mRNA profiling of endometriosis rat uterine tissues during the implantation window

Han Cai, Xinxin Zhu, Zhanfei Li, Yapei Zhu, Jinghe Lang

Pages: 2145-2160 Published online on: 14 October 2019
Open Access

TROP2 increases growth and metastasis of human oral squamous cell carcinoma through activation of the PI3K/Akt signaling pathway

Genxiong Tang, Qi Tang, Lizhou Jia, Yuan Chen, Liangyuan Lin, Xingwang Kuai, Aixiu Gong, Zhengqing Feng

Pages: 2161-2170 Published online on: 21 October 2019
Open Access

Pistacia weinmannifolia root exerts a protective role in ovalbumin‑induced lung inflammation in a mouse allergic asthma model

Jae‑Won Lee, Jae‑Hong Min, Min‑Gu Kim, Seong‑Man Kim, Ok‑Kyoung Kwon, Tae Kyu Oh, Jae Kyoung Lee, Tae Young Kim, Sang Woo Lee, Sangho Choi, Wan‑Yi Li, Hyung Won Ryu, Kyung‑Seop Ahn, Sei‑Ryang Oh

Pages: 2171-2180 Published online on: 07 October 2019
Open Access

Tacrolimus increases the expression level of the chemokine receptor CXCR2 to promote renal fibrosis progression

Dongdong Wang, Xiao Chen, Meng Fu, Hong Xu, Zhiping Li

Pages: 2181-2188 Published online on: 10 October 2019
Open Access

Glutamine affects T24 bladder cancer cell proliferation by activating STAT3 through ROS and glutaminolysis

Ningchuan Sun, Ye Liang, Yuanbin Chen, Liping Wang, Dan Li, Zhijuan Liang, Lijiang Sun, Yonghua Wang, Haitao Niu

Pages: 2189-2200 Published online on: 25 October 2019
Open Access

Role and mechanisms of action of microRNA‑21 as regards the regulation of the WNT/β‑catenin signaling pathway in the pathogenesis of non‑alcoholic fatty liver disease

Xiu‑Mei Wang, Xiao‑Yi Wang, Yu‑Mei Huang, Xia Chen, Mu‑Han Lü, Lei Shi, Chang‑Ping Li

Pages: 2201-2212 Published online on: 18 October 2019
Open Access

Dihydroartemisinin attenuates lipopolysaccharide‑induced acute lung injury in mice by suppressing NF‑κB signaling in an Nrf2‑dependent manner

Xiao‑Ting Huang, Wei Liu, Yong Zhou, Cai‑Xia Hao, Yan Zhou, Chen‑Yu Zhang, Chen‑Chen Sun, Zi‑Qiang Luo, Si‑Yuan Tang

Pages: 2213-2222 Published online on: 29 October 2019
Open Access

Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy

Miriam Carbo, Valentina Brandi, Gianmarco Pascarella, David Sasah Staid, Gianni Colotti, Fabio Polticelli, Andrea Ilari, Veronica Morea

Pages: 2223-2233 Published online on: 15 October 2019
Open Access

Biological effects of melatonin on human adipose‑derived mesenchymal stem cells

June Seok Heo, Sangshin Pyo, Ja‑Yun Lim, Dae Wui Yoon, Bo Yong Kim, Jin‑Hee Kim, Gi Jin Kim, Seung Gwan Lee, Jinkwan Kim

Pages: 2234-2244 Published online on: 27 September 2019
Open Access

Tumor cell‑fibroblast heterotypic aggregates in malignant ascites of patients with ovarian cancer

Qing Han, Bangxing Huang, Zaiju Huang, Jing Cai, Lanqing Gong, Yifan Zhang, Jiahong Jiang, Weihong Dong, Zehua Wang

Pages: 2245-2255 Published online on: 02 October 2019
Open Access

The A3 adenosine receptor agonist, namodenoson, ameliorates non‑alcoholic steatohepatitis in mice

Pnina Fishman, Shira Cohen, Inbal Itzhak, Johnny Amer, Ahmad Salhab, Faina Barer, Rifaat Safadi

Pages: 2256-2264 Published online on: 03 October 2019
Open Access

Influence of radiation exposure pattern on the bone injury and osteoclastogenesis in a rat model

Jianglong Zhai, Feilong He, Jianping Wang, Junxiang Chen, Ling Tong, Guoying Zhu

Pages: 2265-2275 Published online on: 11 October 2019
Open Access

RFC3 induces epithelial‑mesenchymal transition in lung adenocarcinoma cells through the Wnt/β‑catenin pathway and possesses prognostic value in lung adenocarcinoma

Shulei Gong, Xiaohan Qu, Shize Yang, Siyu Zhou, Peiwen Li, Qigang Zhang

Pages: 2276-2288 Published online on: 29 October 2019
Open Access

Rutin promotes the formation and osteogenic differentiation of human periodontal ligament stem cell sheets in vitro

Bin Zhao, Yunpeng Zhang, Yixuan Xiong, Xin Xu

Pages: 2289-2297 Published online on: 25 October 2019

Genistein improves viability, proliferation and mitochondrial function of cardiomyoblasts cultured in physiologic and peroxidative conditions

Serena Farruggio, Giulia Raina, Grazia Cocomazzi, Carlotta Librasi, David Mary, Sergio Gentilli, Elena Grossini

Pages: 2298-2310 Published online on: 03 October 2019

Resveratrol attenuates pulmonary embolism associated cardiac injury by suppressing activation of the inflammasome via the MALAT1‑miR‑22‑3p signaling pathway

Kai Yang, Wancheng Li, Wenjuan Duan, Yi Jiang, Na Huang, Yunhui Li, Bocheng Ren, Jian Sun

Pages: 2311-2320 Published online on: 01 October 2019

Kaempferol‑3‑O‑β‑rutinoside suppresses the inflammatory responses in lipopolysaccharide‑stimulated RAW264.7 cells via the NF‑κB and MAPK pathways

Dukhyun Hwang, Min‑Jae Kang, Chang‑Won Kang, Gun‑Do Kim

Pages: 2321-2328 Published online on: 22 October 2019

Leiomyoma phosphoproteins involved in inhibition of oxidative stress and synthesis of reactive oxygen species

Blendi Ura, Lorenzo Monasta, Giorgio Arrigoni, Danilo Licastro, Giovanni Di Lorenzo, Federico Romano, Bartolomea Gaita, Federica Scrimin, Giuseppe Ricci

Pages: 2329-2335 Published online on: 21 October 2019

Osteoadherin serves roles in the regulation of apoptosis and growth in MC3T3‑E1 osteoblast cells

Eri Hamaya, Toshiaki Fujisawa, Masato Tamura

Pages: 2336-2344 Published online on: 18 October 2019
Journal Cover

December 2019
Volume 44 Issue 6

Print ISSN: 1107-3756
Online ISSN: 1791-244X

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