Journal Articles

Article Open Access

Value of GastroPanel in the diagnosis of atrophic gastritis

Cosmin Grad, Andrei Pop, Emil Gaborean, Simona Grad, Dan Dumitrascu

Article Number: 1347 Published online on: 22 September 2021
Review Open Access

A systematic review of euthyroid Graves' disease (Review)

Mioara-Laura Macovei, Űnal Azis, Alina Gabriela Gheorghe, Marian Burcea

Article Number: 1346 Published online on: 22 September 2021
Review

Pheochromocytoma as a rare hypertensive complication rarely associated with pregnancy: Diagnostic difficulties (Review)

Irina Pacu, Nikolaos Zygouropoulos, Cristian George Furau, Dan Navolan, Delia Mirela Tit, Cringu A. Ionescu, Anca Pantea Stoian, Aida Petca, Mihai Dimitriu

Article Number: 1345 Published online on: 22 September 2021
Review

Prediction of bleeding events using the VTE‑BLEED risk score in patients with venous thromboembolism receiving anticoagulant therapy (Review)

Minerva Codruta Badescu, Manuela Ciocoiu, Oana Viola Badulescu, Maria-Cristina Vladeanu, Iris Bararu Bojan, Cristiana Elena Vlad, Ciprian Rezus

Article Number: 1344 Published online on: 22 September 2021
Article Open Access

MEX3A knockdown inhibits the tumorigenesis of colorectal cancer via modulating CDK2 expression

Xin Zhou, Shaojie Li, Tiexiang Ma, Jian Zeng, Huanyu Li, Xiang Liu, Feng Li, Bin Jiang, Ming Zhao, Zhuo Liu, Yiyu Qin

Article Number: 1343 Published online on: 22 September 2021
Article

Downregulation of MIAT reduces the proliferation and migratory and invasive abilities of retinoblastoma cells by sponging miR‑665 and regulating LASP1

Xiabing Xu, Yadong Zhao, Gang Duan, Bo Du

Article Number: 1342 Published online on: 22 September 2021
Article

Blood glucose control contributes to protein stability of Ski‑related novel protein N in a rat model of diabetes

Luqun Liang, Shuang Li, Huiming Liu, Yanwen Mao, Lingling Liu, Xiaohuan Zhang, Wei Peng, Ying Xiao, Fan Zhang, Mingjun Shi, Yuanyuan Wang, Bing Guo

Article Number: 1341 Published online on: 22 September 2021
Article Open Access

Long non‑coding RNA RP11‑84C13.1 promotes osteogenic differentiation of bone mesenchymal stem cells and alleviates osteoporosis progression via the miR‑23b‑3p/RUNX2 axis

Huaixi Yu, Yunyun Li, Jinshan Tang, Xiaoqing Lu, Wen Hu, Liang Cheng

Article Number: 1340 Published online on: 22 September 2021
Article Open Access

Enhanced expression of KIF4A in osteosarcoma predicts a poor prognosis and facilitates tumor growth by activation of the MAPK pathway

Dongsheng Zhu, Xiangfei Xu, Ming Zhang, Tong Wang

Article Number: 1339 Published online on: 22 September 2021
Review

Adrenal ganglioneuroma: Prognostic factors (Review)

Florica Sandru, Mihai Cristian Dumitrascu, Aida Petca, Mara Carsote, Razvan-Cosmin Petca, Ana Maria Oproiu, Adina Ghemigian

Article Number: 1338 Published online on: 22 September 2021
Article Open Access

Progranulin: A proangiogenic factor in visceral adipose tissue in tumoral and non‑tumoral visceral pathology

Ioana Binișor, Ileana Monica Baniță, Dragoș Alexandru, Mihaela Cezarina Mehedinți, Sanda Jurja, Ana-Marina Andrei, Cătălina Gabriela Pisoschi

Article Number: 1337 Published online on: 22 September 2021
Article Open Access

Predictive factors for the recurrence of surgically excised basal cell carcinomas: A retrospective clinical and immunopathological pilot study

Corina Vornicescu, Simona Corina Șenilă, Nona Ionela Bejinariu, Ștefan Cristian Vesa, Adina Bianca Boșca, Daciana Narcisa Chirilă, Carmen Stanca Melincovici, Olga Sorițău, Carmen Mihaela Mihu

Article Number: 1336 Published online on: 20 September 2021
Review Open Access

Comprehensive review on the pathophysiology, clinical variants and management of pemphigus (Review)

Victor-Vlad Costan, Cristina Popa, Mădălina Florina Hâncu, Elena Porumb‑Andrese, Mihaela Paula Toader

Article Number: 1335 Published online on: 20 September 2021
Review Open Access

Spongiotic reaction patterns in autoimmune bullous dermatoses (Review)

Raluca Anca Balan, Ludmila Lozneanu, Adriana Grigoras, Irina Draga Caruntu, Teodora Ana Balan, Simona Eliza Giusca, Cornelia Amalinei

Article Number: 1334 Published online on: 20 September 2021
Article

Anthropometric and metabolic profile of children with gene polymorphisms for primary lactose intolerance

Corina Pienar, Liviu Pop, Marilena Lăzărescu, Radmila Costăchescu, Edward Șeclăman

Article Number: 1333 Published online on: 20 September 2021
Article Open Access

Effects of Psoralea corylifolia L. seed extract on AGEs‑induced cell proliferation and fibrotic factor expression in mesangial cells

Hyunah Chung, Eunhui Seo, Hee-Sook Jun

Article Number: 1332 Published online on: 20 September 2021
Article

Keratosis pilaris atrophicans faciei: An observational, descriptive, retrospective clinical study

Gyula László Fekete, László Fekete, Nicoleta Neagu, Vladimir Bacârea, Miruna Drăgănescu, Ilarie Brihan

Article Number: 1331 Published online on: 20 September 2021
Review

Skin anomalies in acromegalic patients (Review of the practical aspects)

Florica Sandru, Adelina Popa, Dan Nicolae Paduraru, Alexandru Filipescu, Mara Carsote, Adina Ghemigian

Article Number: 1330 Published online on: 20 September 2021
Review

Modern markers for evaluating bone disease in multiple myeloma (Review)

Vlad Pop, Andrada Parvu, Alexandra Craciun, Anca Daniela Farcas, Gheorghe Tomoaia, Anca Bojan

Article Number: 1329 Published online on: 20 September 2021
Article Open Access

miR‑515‑5p inhibits the proliferation, migration and invasion of human breast cancer cells by targeting CBX4

Liu-Jing Wen, Yue-Sheng Wang, Pei-Yi Tan

Article Number: 1328 Published online on: 20 September 2021
Review

Research progress on evodiamine, a bioactive alkaloid of Evodiae fructus: Focus on its anti‑cancer activity and bioavailability (Review)

Chaodan Luo, Jingwen Ai, Erfang Ren, Jianqiang Li, Chunmei Feng, Xinrong Li, Xiaojie Luo

Article Number: 1327 Published online on: 20 September 2021
Article Open Access

Cycloastragenol and Astragaloside IV activate telomerase and protect nucleus pulposus cells against high glucose‑induced senescence and apoptosis

Haofeng Hong, Jian Xiao, Quanquan Guo, Jinhui Du, Zhichen Jiang, Sisi Lu, Hongyuan Zhang, Xiaolei Zhang, Xiangyang Wang

Article Number: 1326 Published online on: 20 September 2021
Article

Efficacy and safety of tenofovir alafenamide fumarate in nucleoside analogue treatment-naïve patients with chronic hepatitis B

Peng Chen, Wei Wei, Li Jin, Wentao Kuai, Fei Li, Huan Liu, Bei Jiang, Yu Zhu

Article Number: 1325 Published online on: 20 September 2021
Article Open Access

Effects of ulinastatin on renal perfusion evaluated by Doppler ultrasonography in a porcine model of septic shock

Chen-Chen Hang, Yu-Hong Guo, Chun-Sheng Li, Shuo Wang

Article Number: 1324 Published online on: 20 September 2021
Article

Intestinal flora alterations in patients with ulcerative colitis and their association with inflammation

Zhi Feng Dai, Xu Yuan Ma, Rui Lin Yang, Hui Chao Wang, Dan Dan Xu, Jing Nan Yang, Xiao Bing Guo, Shuang Shuang Meng, Rui Xu, Yu Xia Li, Yao Xu, Kun Li, Xu Hong Lin

Article Number: 1322 Published online on: 20 September 2021
Article

Gas6/Axl signaling pathway promotes proliferation, migration and invasion and inhibits apoptosis in A549 cells

Dong Wang, Lixin Bi, Jingping Ran, Lei Zhang, Na Xiao, Xiaoli Li

Article Number: 1321 Published online on: 20 September 2021
Article Open Access

An enriched environment delays the progression from mild cognitive impairment to Alzheimer's disease in senescence‑accelerated mouse prone 8 mice

Jian-Zhong Li, Xing-Hua Hao, Hai-Ping Wu, Ming Li, Xue-Min Liu, Zhi-Bing Wu

Article Number: 1320 Published online on: 20 September 2021
Article Open Access

miR‑638 suppresses proliferation by negatively regulating high mobility group A1 in ovarian cancer cells

Li Ma, Wei Zhang, Yaofeng Jin, Xiaomei Bai, Qiaoling Yu

Article Number: 1319 Published online on: 20 September 2021
Article Open Access

MicroRNA‑18a‑5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression

Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuang

Article Number: 1318 Published online on: 20 September 2021
Article Open Access

Gigantol inhibits cell proliferation and induces apoptosis by regulating DEK in non‑small cell lung cancer

Yuxing Cai, Yi Hao, Hui Xu, Kai Chen, Baozhong Ren

Article Number: 1317 Published online on: 17 September 2021
Article Open Access

Metformin attenuates H2O2‑induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway

Keda Yang, Lei Pei, Siming Zhou, Lin Tao, Yue Zhu

Article Number: 1316 Published online on: 17 September 2021
Review Open Access

Biocompatibility assessment of biomaterials used in orthopedic devices: An overview (Review)

Bogdan Huzum, Bogdan Puha, Riana Maria Necoara, Stefan Gheorghevici, Gabriela Puha, Alexandru Filip, Paul Dan Sirbu, Ovidiu Alexa

Article Number: 1315 Published online on: 17 September 2021
Review

Neoadjuvant intraperitoneal chemotherapy for advanced stage gastric cancer (Review)

Nicolae Bacalbasa, Camelia Diaconu, Bogdan Socea, Florentina Gherghiceanu, Cornel Savu, Mihai Dimitriu, Irina Balescu, Ioan Cordos

Article Number: 1314 Published online on: 17 September 2021
Review

Dermatological and endocrine elements in Carney complex (Review)

Florica Sandru, Mihai Cristian Dumitrascu, Aida Petca, Mara Carsote, Razvan-Cosmin Petca, Diana Loreta Paun

Article Number: 1313 Published online on: 17 September 2021
Article Open Access

Dietary Bacillus subtilis supplementation alleviates alcohol‑induced liver injury by maintaining intestinal integrity and gut microbiota homeostasis in mice

Meiqi Zhao, Chuanai Chen, Zhoujie Yuan, Wenwen Li, Mohan Zhang, Nailing Cui, Yitao Duan, Xiaoqian Zhang, Peng Zhang

Article Number: 1312 Published online on: 16 September 2021
Article Open Access

HOXC11 positively regulates the long non-coding RNA HOTAIR and is associated with poor prognosis in colon adenocarcinoma

Nana Gong, Fei Li, Yanan Wang, Zizi Li, Wanqiu Wang, Tingting Gong, Xiaojun Meng, Hongtao Chen

Article Number: 1310 Published online on: 16 September 2021
Article Open Access

Matrine ameliorates the inflammatory response and lipid metabolism in vascular smooth muscle cells through the NF‑κB pathway

Guanglei Wang, Chengyu Ji, Chunling Wang, Zhonghui Liu, Aizhong Qu, Huaixin Wang

Article Number: 1309 Published online on: 16 September 2021
Article Open Access

Yiqi Huoxue preserves heart function by upregulating the Sigma‑1 receptor in rats with myocardial infarction

Lixia Lou, Chunhong Li, Jie Wang, Aiming Wu, Ting Zhang, Zhe Ma, Limin Chai, Dongmei Zhang, Yizhou Zhao, Bo Nie, Qiushuo Jin, Huiyang Chen, Wei Jing Liu

Article Number: 1308 Published online on: 16 September 2021
Article Open Access

Ononin alleviates H2O2‑induced cardiomyocyte apoptosis and improves cardiac function by activating the AMPK/mTOR/autophagy pathway

Rongrong Pan, Qin Zhuang, Jiangtin Wang

Article Number: 1307 Published online on: 16 September 2021
Article Open Access

Maiwei Yangfei decoction prevents bleomycin‑induced pulmonary fibrosis in mice

Yong Xu, Wenpan Peng, Di Han, Fanchao Feng, Zhichao Wang, Cheng Gu, Xianmei Zhou, Qi Wu

Article Number: 1306 Published online on: 16 September 2021
Article Open Access

Anticancer roles of let‑7f‑1‑3p in non‑small cell lung cancer via direct targeting of integrin β1

Yanan Yang, Yuanrong Liu, Ning Xie, Liying Shao, Hang Sun, Yubo Wei, Yunxiao Sun, Pingyu Wang, Yunfei Yan, Shuyang Xie, Youjie Li

Article Number: 1305 Published online on: 16 September 2021
Article Open Access

Exosomes derived from PC‑3 cells suppress osteoclast differentiation by downregulating miR‑148a and blocking the PI3K/AKT/mTOR pathway

Gaoqiang Tian, Konghe Hu, Sujun Qiu, Yingming Xie, Yanlin Cao, Songjia Ni, Lifang Zhang

Article Number: 1304 Published online on: 16 September 2021
Article Open Access

Insulin receptor substrate‑1 and dishevelled 2 are negatively regulated by microRNA‑144 and inhibit nasopharyngeal carcinoma cell malignancy

Xuemei An, Yunlan Jiang, Defeng Chen, Jianjun Chen

Article Number: 1303 Published online on: 16 September 2021
Article Open Access

Panax notoginseng saponins alleviate osteoporosis and joint destruction in rabbits with antigen‑induced arthritis

Chen Chao Wei, Li Fei Yue, Fan Tian You, Che Tao

Article Number: 1302 Published online on: 16 September 2021
Article

Honokiol combined with curcumin sensitizes multidrug‑resistant human lung adenocarcinoma A549/DDP cells to cisplatin

Mingming Qi, Xiaojin Chen, Liqun Bian, Han Zhang, Jian Ma

Article Number: 1301 Published online on: 16 September 2021
Article

Effects of isoflavone derivatives on the production of inflammatory cytokines by synovial cells

Nuerbiyemu Mijiti, Akimasa Someya, Isao Nagaoka

Article Number: 1300 Published online on: 16 September 2021
Article Open Access

TFAP4 promotes the growth of prostate cancer cells by upregulating FOXK1

Yuan Gu, Jiujin Jiang, Chaozhao Liang

Article Number: 1299 Published online on: 16 September 2021
Article Open Access

Patients affected by squamous cell carcinoma of the head and neck: A population particularly prone to developing severe forms of COVID‑19

Francesco Perri, Anna Crispo, Franco Ionna, Paolo Muto, Francesco Caponigro, Francesco Longo, Concetta Montagnese, Pierluigi Franco, Ettore Pavone, Corrado Aversa, Agostino Guida, Sabrina Bimonte, Alessandro Ottaiano, Massimiliano Di Marzo, Giuseppe Porciello, Alfonso Amore, Egidio Celentano, Giuseppina Della Vittoria Scarpati, Marco Cascella

Article Number: 1298 Published online on: 16 September 2021
Review

Renal tumor biomarkers (Review)

Ovidiu Bratu, Dan Mischianu, Dragos Marcu, Dan Spinu, Lucian Iorga, Alexandru Cherciu, Irina Balescu, Nicolae Bacalbasa, Camelia Diaconu, Cornel Savu, Carmen Savu, Radu Anghel

Article Number: 1297 Published online on: 14 September 2021
Review Open Access

Extracorporeal membrane oxygenation in the management of critically ill patients with coronavirus disease 2019: A narrative review

Alexandru Florin Pleșoianu, Carmen Elena Pleșoianu, Iris Bararu‑Bojan (Bararu), Maria-Cristina Vlădeanu (Apăvăloaei), Andrei Bojan, Andrei Țăruș, Grigore Tinică

Article Number: 1296 Published online on: 14 September 2021
Article Open Access

Ubisol Coenzyme Q10 promotes mitochondrial biogenesis in HT22 cells challenged by glutamate

Mary A. Zimmerman, Mia Hall, Qi Qi, Suresh L. Mehta, Guisheng Chen, P. Andy Li

Article Number: 1295 Published online on: 14 September 2021
Retraction Open Access

[Retracted] MicroRNA‑33b inhibits cell proliferation and glycolysis by targeting hypoxia‑inducible factor‑1α in malignant melanoma

Yue Zhao, Cuiling Wu, Lina Li

Article Number: 1294 Published online on: 13 September 2021
Retraction Open Access

[Retracted] MicroRNA‑30a‑5p inhibits the proliferation and invasion of gastric cancer cells by targeting insulin‑like growth factor 1 receptor

Yang Liu, Yu Zhou, Xun Gong, Changjie Zhang

Article Number: 1293 Published online on: 13 September 2021
Review Open Access

Brain‑derived neurotrophic factor in autoimmune inflammatory diseases (Review)

Ningning Wang, Bailing Tian

Article Number: 1292 Published online on: 13 September 2021
Article Open Access
Article Open Access

LIPOSA pharmacopuncture, a new herbal formula, affects localized adiposity by regulating lipid metabolism in vivo

Haesu Lee, Mi Hye Kim, Seong Chul Jin, La Yoon Choi, Yeon Kyung Nam, Woong Mo Yang

Article Number: 1290 Published online on: 13 September 2021
Article Open Access

Role of caveolin‑1 in chronic postsurgical pain in rats

Sai-Sai Huang, Su Cao, Yi-Bin Qin, Cui E. Lu, Shi-Ren Shen

Article Number: 1289 Published online on: 13 September 2021
Article Open Access

MicroRNA‑24 protects against myocardial ischemia‑reperfusion injury via the NF‑κB/TNF‑α pathway

Chenlei Li, Ming Fang, Zhikang Lin, Wenhui Wang, Xinming Li

Article Number: 1288 Published online on: 13 September 2021
Article Open Access

Sinomenine hydrochloride ameliorates dextran sulfate sodium‑induced colitis in mice by modulating the gut microbiota composition whilst suppressing the activation of the NLRP3 inflammasome

Yan Zhou, Shuai Chen, Wenxian Gu, Xiao Sun, Linxiao Wang, Liming Tang

Article Number: 1287 Published online on: 13 September 2021
Case Report Open Access

Leiomyoma of the uterine round ligament: A case report

Aliki Tympa, Charalampos Grigoriadis, Emmanouil Terzakis, Christina Goudeli, Aikaterini Melemeni

Article Number: 1285 Published online on: 13 September 2021
Article

Prognostic value of miR‑1181 in non‑small cell lung cancer and its regulatory effect on tumor progression

Feng Liu, Guodong Ma, Bo Wang, Xiang Wang, Chenjun Huang

Article Number: 1284 Published online on: 13 September 2021
Review Open Access

Evaluation of the SF‑36 questionnaire for assessment of the quality of life of endometriosis patients undergoing treatment: A systematic review and meta‑analysis

Romina-Marina Sima, Liana Pleş, Bogdan Socea, Panagiotis Sklavounos, Ionuţ Negoi, Anca-Daniela Stănescu, Ioan-Iulian Iordache, Bashar Haj Hamoud, Marc Phillip Radosa, Ingolf Juhasz‑Boess, Erich Franz Solomayer, Mihai C.T. Dimitriu, Cătălin Cîrstoveanu, Dragoş Şerban, Julia Caroline Radosa

Article Number: 1283 Published online on: 13 September 2021
Article Open Access

Sequential growth factor exposure of human Ad‑MSCs improves chondrogenic differentiation in an osteochondral biphasic implant

Alejandro Garcia‑Ruiz, Celia N. Sánchez‑Domínguez, Nidia K. Moncada‑Saucedo, Vanessa Pérez‑Silos, Jorge Lara‑Arias, Iván A. Marino‑Martínez, Alberto Camacho‑Morales, Víktor J. Romero‑Diaz, Víctor Peña‑Martinez, Rosalío Ramos‑Payán, Yanko Castro‑Govea, Rocky S. Tuan, Hang Lin, Lizeth Fuentes‑Mera, Ana María Rivas‑Estilla

Article Number: 1282 Published online on: 13 September 2021
Review Open Access

Efficacy of electroconvulsive therapy as a potential first‑choice treatment in treatment‑resistant depression (Review)

Simona Trifu, Anca Sevcenco, Monica Stănescu, Ana Miruna Drăgoi, Mihai Bogdan Cristea

Article Number: 1281 Published online on: 09 September 2021
Retraction Open Access

[Retracted] Paraptosis triggers mitochondrial pathway‑mediated apoptosis in Alzheimer’s disease

Dong-Pei Jia, Song Wang, Bao-Chao Zhang, Fang Fang

Article Number: 1280 Published online on: 09 September 2021
Review Open Access

Role of circular RNAs in osteoarthritis (Review)

Jicheng Wang, Bo Yang, Changkun Wu, Yongzhi Guo, Xin Jiang, Yangyang Zhang

Article Number: 1279 Published online on: 09 September 2021
Article Open Access

miR‑122‑5p downregulation attenuates lipopolysaccharide‑induced acute lung injury by targeting IL1RN

Jie Li, Xiaoxia Zeng, Weiqing Wang

Article Number: 1278 Published online on: 08 September 2021
Case Report Open Access

Vasculitis associated with the use of an intrauterine device: A case report

Aurelian Mihai Ghita, Cristina Alexandrescu, Sanziana Istrate, Anca Evsei, Ana Cristina Ghita

Article Number: 1277 Published online on: 08 September 2021
Article Open Access

circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo

Article Number: 1276 Published online on: 08 September 2021
Article Open Access

Novel function of fluvastatin in attenuating oxidized low‑density lipoprotein‑induced endothelial cell ferroptosis in a glutathione peroxidase4‑ and cystine‑glutamate antiporter‑dependent manner

Qing Li, Chang Liu, Liang Deng, Enrui Xie, Nishant Yadav, Yuanyuan Tie, Zheng Cheng, Jie Deng

Article Number: 1275 Published online on: 08 September 2021
Article Open Access

LINC00963 silencing inhibits the proliferation and migration of high glucose‑induced retinal endothelial cells via targeting miR‑27b

Rui Zhang, Chunhong Niu, Yuhan Guan, Jianhua Wu, Liping Hu

Article Number: 1274 Published online on: 08 September 2021
Article
Article

Frequent injections of high‑dose human umbilical cord mesenchymal stem cells slightly aggravate arthritis and skeletal muscle cachexia in collagen‑induced arthritic mice

Lemei An, Tianshu Chu, Liujun Wang, Songtao An, Yalong Li, Hongbo Hao, Zhuoli Zhang, Han Yue

Article Number: 1272 Published online on: 07 September 2021
Article Open Access

TFEC contributes to cardiac hypertrophy by inhibiting AMPK/mTOR signaling

Ting Zhao, Zhenyu Wang, Yehong Chi, Chunmei Ni, Xudan Zheng

Article Number: 1271 Published online on: 07 September 2021
Review Open Access

Emerging roles of growth differentiation factor‑15 in brain disorders (Review)

Wei-Wei Jiang, Zi-Zhen Zhang, Ping-Ping He, Li-Ping Jiang, Jin-Zhi Chen, Xing-Ting Zhang, Mi Hu, Yang-Kai Zhang, Xin-Ping Ouyang

Article Number: 1270 Published online on: 07 September 2021
Article Open Access

Se alleviates homocysteine‑induced fibrosis in cardiac fibroblasts via downregulation of lncRNA MEG3

Wei Li, Yuanhong Li, Shengyu Cui, Jiayi Liu, Lijiao Tan, Hao Xia, Changjiang Zhang

Article Number: 1269 Published online on: 07 September 2021
Review Open Access

Association between obesity and iron deficiency (Review)

Naseem Mohammad Alshwaiyat, Aryati Ahmad, Wan Mohd Razin Wan Hassan, Hamid Ali Nagi Al‑Jamal

Article Number: 1268 Published online on: 07 September 2021
Review

Determination of whether HIPEC is beneficial in patients with synchronous peritoneal and liver metastases from colorectal cancer (Review)

Nicolae Bacalbasa, Irina Balescu, Dragos Cretoiu, Ioana Halmaciu, Mihai Dimitriu, Bogdan Socea, Camelia Diaconu, Laura Iliescu, Cornel Savu, Carmen Savu, Alexandru Filipescu, Claudia Stoica, Ovidiu Stiru

Article Number: 1267 Published online on: 07 September 2021
Review

HPV vaccine for men: Where to? (Review)

Arsenie Dan Spînu, Radu Florentin Anghel, Dragoș Radu Marcu, Daniel Lucian Iorga, Alexandru Cherciu, Dan Liviu Dorel Mischianu

Article Number: 1266 Published online on: 07 September 2021
Article Open Access

Insulin‑like growth factor 1 promotes neurological functional recovery after spinal cord injury through inhibition of autophagy via the PI3K/Akt/mTOR signaling pathway

Duo Zhang, Yuan Yuan, Jichao Zhu, Di Zhu, Chenxi Li, Wei Cui, Lei Wang, Song Ma, Shuo Duan, Baoge Liu

Article Number: 1265 Published online on: 06 September 2021
Review Open Access

Current diagnosis and treatment of rhinosinusal aspergilloma (Review)

Daniela Vrinceanu, Mihai Dumitru, Oana Maria Patrascu, Adrian Costache, Toma Papacocea, Romica Cergan

Article Number: 1264 Published online on: 06 September 2021
Review Open Access

Biological therapies targeting the type 2 inflammatory pathway in severe asthma (Review)

Ariadna Petronela Fildan, Ruxandra-Mioara Rajnoveanu, Roxana Cirjaliu, Ionela Pohrib, Emanuela Tudorache, Adrian Cosmin Ilie, Cristian Oancea, Doina Tofolean

Article Number: 1263 Published online on: 06 September 2021
Article Open Access

Autophagy is involved in neurofibromatosis type I gene‑modulated osteogenic differentiation in human bone mesenchymal stem cells

Yiqiang Li, Mingwei Zhu, Xuemei Lin, Jingchun Li, Zhe Yuan, Yanhan Liu, Hongwen Xu

Article Number: 1262 Published online on: 06 September 2021
Article

The added value of three‑dimensional ultrasonography in uterine pathology

Mihaela Grigore, Razvan Popovici, Loredana Maria Himiniuc, Ioana Sadiye Scripcariu, Bogdan Florin Toma, Ana Maria Grigore, Mihaela Oancea, Romeo Micu

Article Number: 1261 Published online on: 06 September 2021
Article Open Access

Quercetin suppresses inflammatory cytokine production in rheumatoid arthritis fibroblast‑like synoviocytes

Hai-Tao Sun, Jian-Peng Li, Wei-Qing Qian, Meng-Fan Yin, Hong Yin, Gui-Cheng Huang

Article Number: 1260 Published online on: 06 September 2021
Article Open Access

Gentianella acuta mitigates cardiovascular damage and inflammation in diet‑induced hypercholesterolaemic rats

Mingdong Si, Meng Wu, Yingying Huo, Aiying Li, Shengjiang Guan, Donglai Ma, Zhihong Ma

Article Number: 1259 Published online on: 06 September 2021
Retraction Open Access

[Retracted] MicroRNA‑92b promotes cell proliferation and invasion in osteosarcoma by directly targeting Dickkopf‑related protein 3

Qing Wu, Wei Zhou, Qiong Feng, Xing Liu, Yanfei Xiong, Hui Li

Article Number: 1258 Published online on: 03 September 2021
Retraction Open Access
Article Open Access

Construction of a new cervical anatomically adaptive titanium mesh cage based on measurements of cervical geometry: A morphological and cadaveric study

Teng Lu, Zhongyang Gao, Jialiang Li, Ning Liu, Yibin Wang, Chao Liu, Xijing He

Article Number: 1256 Published online on: 03 September 2021
Article Open Access

Consistency of pituitary adenomas: Amounts of collagen types I and III and the predictive value of T2WI MRI

Peiliang Li, Dainan Zhang, Shunchang Ma, Peng Kang, Chuanbao  Zhang, Beibei Mao, Wenjianlong Zhou, Xi Wang, Jiayi  Peng, Linhao  Yuan, Yangyang Wang, Jinfu Diao, Wang Jia

Article Number: 1255 Published online on: 03 September 2021
Article Open Access

Etomidate inhibits cell proliferation and induces apoptosis in A549 non‑small cell lung cancer cells via downregulating WWP2

Deqiang Li, Junlong Zhang, Lijun Yin, Zhen Jin, Xuejun Chen, Xiangxue Meng

Article Number: 1254 Published online on: 03 September 2021
Article Open Access

Antibodies against thyroid‑stimulating hormone receptor cause maternal‑neonatal transmission of Graves' Disease

Yue Yu, Qian-Qi Liu, De-Yun Liu, Dan-Dan Wang, Li-Qi Yang, Shu-Ming Ye

Article Number: 1253 Published online on: 03 September 2021
Article Open Access

Evidence‑based complementary and alternative medicine bioinformatics approach through network pharmacology and molecular docking to determine the molecular mechanisms of Erjing pill in Alzheimer's disease

Xiyang Yang, Yang Guan, Bo Yan, Yongyan Xie, Maofu Zhou, Yi Wu, Lihua Yao, Xiaopeng Qiu, Feixia Yan, Yaohui Chen, Liping Huang

Article Number: 1252 Published online on: 02 September 2021
Article Open Access

Role of miR‑139‑5p in ectopic endometrial stromal cells and the underlying molecular mechanism

Lixia Feng, Xu Chen, Shenghua Zhang, Yunxia Chen, Yanling Yu

Article Number: 1251 Published online on: 02 September 2021
Article Open Access

Prediction of in‑hospital recurrence and false‑negative results in patients with COVID‑19 by red blood cell values on admission

Xue Jiang, Yan Hu, Xiao-Peng Qu, Dong-Wei Xu, Hong Jiang, Chun-Mei Li, Hua Jiang, Da-Li Wang, Gang Li, Xin-Gen Zhu, Bei Liu

Article Number: 1250 Published online on: 02 September 2021
Article Open Access

Butorphanol alleviates lipopolysaccharide‑induced inflammation and apoptosis of cardiomyocytes via activation of the κ‑opioid receptor

Weiqing Tang, Liu Luo, Baoji Hu, Mingzhi Zheng

Article Number: 1248 Published online on: 02 September 2021
Article Open Access

LINC00473 exacerbates osteoarthritis development by promoting chondrocyte apoptosis and proinflammatory cytokine production through the miR‑424‑5p/LY6E axis

Guiyong Fan, Jinlian Liu, Yesong Zhang, Xinxian Guan

Article Number: 1247 Published online on: 02 September 2021
Article Open Access

Suppressing TRAP1 sensitizes glioblastoma multiforme cells to temozolomide

Nan Wang, Peining Zhu, Renxuan Huang, Liankun Sun, Delu Dong, Yufei Gao

Article Number: 1246 Published online on: 02 September 2021
Article Open Access

Knockdown of DLGAP5 suppresses cell proliferation, induces G2/M phase arrest and apoptosis in ovarian cancer

Huijun Zhang, Yuan Liu, Shengchun Tang, Xiaomin  Qin, Lin  Li, Jinting Zhou, Jing Zhang, Bo Liu

Article Number: 1245 Published online on: 02 September 2021
Article

Knockdown of LINC01385 inhibits osteoarthritis progression by modulating the microRNA‑140‑3p/TLR4 axis

Zidong Wang, Chuanwang Huang, Cunju Zhao, Huiling Zhang, Zhen Zhen, Duliang Xu

Article Number: 1244 Published online on: 02 September 2021
Review Open Access

Regulatory effect of insulin on the structure, function and metabolism of Na+/K+‑ATPase (Review)

Xu-Peng Wen, Qi-Quan Wan

Article Number: 1243 Published online on: 01 September 2021
Article

Inhibitory effect of tumor necrosis factor‑α on the basolateral Kir4.1/Kir5.1 channels in the thick ascending limb during diabetes

Guoyan Zhang, Zhiming Lv, Yang Zhao, Rui Chen, Xiangyu Zhan, Weiqun Wang, Hongyu Sui

Article Number: 1242 Published online on: 01 September 2021
Article Open Access

Protective effect of 18β‑glycyrrhetinic acid against H2O2‑induced injury in Schwann cells based on network pharmacology and experimental validation

Di Zhang, Jianxin Sun, Shiquan Chang, Xing Li, Huimei Shi, Bei Jing, Yachun Zheng, Yi Lin, Guoqiang Qian, Yuwei Pan, Guoping Zhao

Article Number: 1241 Published online on: 01 September 2021
Article Open Access

Involvement of bradykinin and bradykinin B1 receptor in patients with endometriosis

Xin Meng, Ying Li, Qingxue Li, Jian Yang, Mingli An, Xinping Fu, Shuancheng Zhang, Jingwei Chen

Article Number: 1240 Published online on: 01 September 2021
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Real‑life Cretan asthma registry focused on severe asthma: On behalf of ‘The Cretan registry of the use of Biologics in Severe Asthma’

Katerina M. Antoniou, Maria Bolaki, Konstantinos Karagiannis, Athina Trachalaki, Despo Ierodiakonou, Vagia Stamatopoulou, Charito Chatzinikolaou, Semeli Mastrodimou, Evangelia Stamataki, George Pitsidianakis, Irini Lambiri, Ioanna Mitrouska, Demetrios A. Spandidos, Nikolaos Tzanakis

Article Number: 1239 Published online on: 01 September 2021
Article Open Access

Rapid detection of human heart‑type fatty acid‑binding protein in human plasma and blood using a colloidal gold‑based lateral flow immunoassay

Yang-Guang Ren, Mei-Chen Liu, Meng-Zhen Ji, Chen Chen, Hang-Zhan Hu, Zi-Xuan Wang, Pin-Qian Yu, Jia-Ming Shang, Qian-Wen Zhou, Ning-Ya Tao, Ya-Fei Guo, Yan-Jiao Lu, Zhi-Zeng Wang

Article Number: 1238 Published online on: 31 August 2021
Article Open Access

Long non‑coding RNA miR155HG silencing restrains ovarian cancer progression by targeting the microRNA‑155‑5p/tyrosinase‑related protein 1 axis

Aiping Wen, Le Luo, Chengchao Du, Xin Luo

Article Number: 1237 Published online on: 31 August 2021
Review Open Access

Role of protein phosphatase 2A in kidney disease (Review)

Lishi Shao, Yiqun Ma, Qixiang Fang, Ziye Huang, Shanshan Wan, Jiaping Wang, Li Yang

Article Number: 1236 Published online on: 31 August 2021
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Neuroprotective role of epigallocatechin‑3‑gallate in acute glaucoma via the nuclear factor‑κB signalling pathway

Wen-Hua Zhang, Yu Chen, Li-Mo Gao, Yan-Na Cao

Article Number: 1235 Published online on: 31 August 2021
Article Open Access

Geniposide protects pulmonary arterial smooth muscle cells from lipopolysaccharide‑induced injury via α7nAchR‑mediated TLR‑4/MyD88 signaling

San-Ying Shen, Li-Quan Ren, Hui-Dong Chen, Hong-Fei Zhu, Deng-Feng Zhou, Bo Zhang, Xiao-Qin Tan, Yong-Hua Xie

Article Number: 1234 Published online on: 31 August 2021
Article

TNFα regulates the expression of the CSE gene in HUVEC

Maoxian Wang

Article Number: 1233 Published online on: 31 August 2021
Review

Benefits of α‑lipoic acid in high‑risk pregnancies (Review)

Aida Petca, Mihaela Bot, Nicoleta Maru, Ioana Gabriela Calo, Andreea Borislavschi, Mihai Cristian Dumitrascu, Razvan-Cosmin Petca, Florica Sandru, Mona Elena Zvanca

Article Number: 1232 Published online on: 31 August 2021
Article Open Access

Metformin attenuates angiotensin II‑induced cardiomyocyte hypertrophy by upregulating the MuRF1 and MAFbx pathway

Fawang Du, Yalin Cao, Yan Ran, Qiang Wu, Baolin Chen

Article Number: 1231 Published online on: 31 August 2021
Article Open Access

Moxibustion improves ovarian function based on the regulation of the androgen balance

Xun Jin, Jie Cheng, Jie Shen, Xing Lv, Qian Li, Yanyun Mu, Hua Bai, Yan Liu, Youbing Xia

Article Number: 1230 Published online on: 30 August 2021
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Long non‑coding RNA TUG1 accelerates abnormal growth of airway smooth muscle cells in asthma by targeting the miR‑138‑5p/E2F3 axis

Haiyin Zhou, Caixia Long, Pingping Liu, Yanying Chen, Lan Luo, Zhenghui Xiao

Article Number: 1229 Published online on: 27 August 2021
Article Open Access

LINC01094 promotes the invasion of ovarian cancer cells and regulates the Wnt/β‑catenin signaling pathway by targeting miR‑532‑3p

Haiyan Chen, Yanlin Liu, Ping Liu, Qiuxiang Dai, Peiliang Wang

Article Number: 1228 Published online on: 27 August 2021
Article Open Access

Upregulating miR‑27a‑3p inhibits cell proliferation and inflammation of rheumatoid arthritis synovial fibroblasts through targeting toll‑like receptor 5

Lifeng Chen, Qiping Lu, Jianhua Chen, Ruibing Feng, Chenxi Yang

Article Number: 1227 Published online on: 27 August 2021
Article Open Access

IL‑1α, IL‑6 and IL‑8 serum values in patients with chronic suppurative otitis media

Roxana Serban, Cristiana Filip, Luminita Mihaela Radulescu, Minerva Codruta Badescu, Magda Mariana Badescu, Bogdan Mihail Diaconescu, Mihail Dan Cobzeanu, Bogdan Mihail Cobzeanu

Article Number: 1226 Published online on: 27 August 2021
Article Open Access

Antipsychotic polypharmacy in adult patients diagnosed with schizophrenia: A retrospective study

Bogdan Patrichi, Cristiana Ţăpoi, Radu Ştefan Rogojină, Irina Bedreagă, Anca Dumitrache, Andreea Itu, Radu Dragomir, Adela-Georgiana Buciuc

Article Number: 1225 Published online on: 27 August 2021
Article Open Access

COL4A1 as a novel oncogene associated with the clinical characteristics of malignancy predicts poor prognosis in glioma

Hongbo Wang, Zhendong Liu, Ang Li, Jialin Wang, Jiantao Liu, Binfeng Liu, Xiaoyu Lian, Bo Zhang, Bo Pang, Liyun Liu, Yanzheng Gao

Article Number: 1224 Published online on: 27 August 2021
Article Open Access

Anti‑inflammatory effects and enhancing immune response of freshwater hybrid catfish oil in RAW264.7 cells

Bussarin Tongmee, Atcharaporn Ontawong, Narissara Lailerd, Kriangsak Mengamphan, Doungporn Amornlerdpisan

Article Number: 1223 Published online on: 26 August 2021
Article Open Access

Resolvin D2 suppresses NLRP3 inflammasome by promoting autophagy in macrophages

Lijun Cao, Yiya Wang, Yina Wang, Feijuan Lv, Lixiu Liu, Zhen Li

Article Number: 1222 Published online on: 26 August 2021
Review Open Access

Roles of circular RNAs in the pathogenesis of intervertebral disc degeneration (Review)

Zhidi Lin, Feizhou Lu, Xiaosheng Ma, Xinlei Xia, Fei Zou, Jianyuan Jiang

Article Number: 1221 Published online on: 26 August 2021
Article Open Access

Mangiferin inhibits hypoxia/reoxygenation‑induced alveolar epithelial cell injury via the SIRT1/AMPK signaling pathway

Xianfeng Chen, Juanjuan Huang

Article Number: 1220 Published online on: 26 August 2021
Review

Neuroendocrine neoplasia and bone (Review)

Adina Ghemigian, Mara Carsote, Florica Sandru, Razvan-Cosmin Petca, Ana-Maria Oproiu, Aida Petca, Ana Valea

Article Number: 1219 Published online on: 26 August 2021
Article

Accelerated lipid peroxidation in a rat model of gentamicin nephrotoxicity

Anamaria Magdalena Tomşa, Andreea Liana Răchişan, Stanca Lucia Pandrea, Andreea Benea, Ana Uifălean, Alina Elena Parvu, Lia Monica Junie

Article Number: 1218 Published online on: 26 August 2021
Article

Ovarian cancer health politics in Romania and Germany: A comparative study

Ionut Marcel Cobec, Ioan Sas, Aurica Elisabeta Moatar, Lavinia Moleriu, Andreas Rempen

Article Number: 1217 Published online on: 26 August 2021
Article Open Access

Analysis of long‑term functional results of radical mastoidectomy

Horia Mocanu, Adela-Ioana Mocanu, Alexandru Bonciu, Gabriella Coadă, Mihai-Adrian Schipor, Marian Rădulescu

Article Number: 1216 Published online on: 26 August 2021
Article Open Access

Impact of COVID‑19 prevention measures on Clostridioides difficile infections in a regional acute care hospital

Simona Sipos, Cristian Vlad, Radu Prejbeanu, Horia Haragus, Daliborca Vlad, Horia Cristian, Cristian Dumitrascu, Roxana Popescu, Victor Dumitrascu, Vlad Predescu

Article Number: 1215 Published online on: 26 August 2021
Article Open Access

Correlation between metabolic status and diabetic retinopathy evolution in type 1 diabetes

Aurelia Romila, Vasile Potop, Radu Ciuluvica, Banita Monica, Mihaela Cezarina Mehedinti Hincu, Sanda Jurja

Article Number: 1214 Published online on: 26 August 2021
Article Open Access

Anti‑inflammation treatment for protection of hepatocytes and amelioration of hepatic fibrosis in rats

Shi Feng, Huan Tong, Jin-Hang Gao, Shi-Hang Tang, Wen-Juan Yang, Gui-Ming Wang, Hong-Ying Zhou, Shi-Lei Wen

Article Number: 1213 Published online on: 24 August 2021
Article Open Access

Heme oxygenase‑1 alleviates advanced glycation end product‑induced oxidative stress, inflammatory response and biological behavioral disorders in rat dermal fibroblasts

Qingling Li, Shangyan Liang, Qianwei Lai, Lishan Shen, Yong Zhang, Ruomi Guo

Article Number: 1212 Published online on: 24 August 2021
Article Open Access

HBxAg promotes HBV replication and EGFR activation in human placental trophoblasts

Yayun Lin, Yan Liu, Dongping Xu, Fanfan Guo, Wentao Zhang, Yidan Zhang, Guiqin Bai

Article Number: 1211 Published online on: 24 August 2021
Article Open Access

Linc8986 and linc0597 in plasma are novel biomarkers for systemic lupus erythematosus

Chunli Rong, Huafeng Xu, Changxin Yan, Feng Wei, Haizhou Zhou, Xiuru Guan

Article Number: 1210 Published online on: 24 August 2021
Article Open Access

Downregulation of microRNA‑96‑5p protects TM3 cells against zearalenone toxicity via targeting ATG9A

Xiaoyuan Xu, Xiaohua Xu, Yanluan Zheng, Lan Xu

Article Number: 1209 Published online on: 24 August 2021
Article Open Access

hsa‑miR‑15b‑5p regulates the proliferation and apoptosis of human vascular smooth muscle cells by targeting the ACSS2/PTGS2 axis

Shujie Gan, Jieqi Mao, Yuqin Pan, Jingdong Tang, Zhengjun Qiu

Article Number: 1208 Published online on: 24 August 2021
Article

Overexpression of miR‑133b protects against isoflurane‑induced learning and memory impairment

Yu Zhang, Jinyong Liu, Cuili Xie, Pingping Wu

Article Number: 1207 Published online on: 24 August 2021
Review

Current research developments of patient‑derived tumour xenograft models (Review)

Zhenyu Yin, Ewetse Paul Maswikiti, Qian Liu, Yuping Bai, Xiaomei Li, Wenbo Qi, Le Liu, Yanling Ma, Hao Chen

Article Number: 1206 Published online on: 24 August 2021
Article Open Access

miR‑28‑3p inhibits prostate cancer cell proliferation, migration and invasion, and promotes apoptosis by targeting ARF6

Jiabin Zhang, Yi Yao, Huizhang Li, Shihua Ye

Article Number: 1205 Published online on: 24 August 2021
Article

Gain of TPPP as a predictor of progression in patients with bladder cancer

Ying-Hsu Chang, Po-Hung Lin, Chin-Chang Chen, Wen-Hui Weng, Kai-Jie Yu, Chung-Yi Liu, Chin-Hsuan Hsieh, Tzu-Hsuan Chang, I-Hung Shao, Hung-Cheng Kan, Cheng-Keng Chuang, See-Tong Pang

Article Number: 1204 Published online on: 24 August 2021
Article Open Access

Podofilox suppresses gastric cancer cell proliferation by regulating cell cycle arrest and the c‑Myc/ATG10 axis

Juan An, Yan Liu, Shenglan Duo, Xiaoming Ma, Ling An, Yunfei Yan, Dongde Ji, Yupeng Yan, Qiliang Cheng, Zhanhai Su

Article Number: 1203 Published online on: 23 August 2021
Article Open Access

lncRNA LOC339524 inhibits the proliferation of bladder cancer cells by targeting the miR‑875‑5p/COPS7A signaling axis

Xuan He, He Xiao, Rui Yang, Hang Chen, Bin Wang

Article Number: 1202 Published online on: 23 August 2021
Article Open Access

Regulatory role of microRNA‑320 during off‑pump coronary artery bypass grafting with dexmedetomidine adjunct anesthesia

Yan Gao, Xiaolong Zhu, Huidan Yu, Wenlong Wang, Yeming Wang, Fulong Li, Jinliang Teng

Article Number: 1201 Published online on: 23 August 2021
Article Open Access

CXCR4 protects bone marrow‑derived endothelial progenitor cells against hypoxia through the PI3K/Akt signaling pathway

Zheng-Yu Liu, Qiu-Xia Yang, Yan Cao, Hong-Wei Pan, Jing-Jing Rong, Jing Ling, Yi Tang, Jin He, Chang-Lu Wang, Xiang Peng, Qiong-Chao Zou, Le Zhang, Jiao Zheng, Jia Wang, Yu Zhang, Jian-Qiang Peng, Lan-Bing Xiong, Feng Liu, Zi-Hui Ying, Zhao-Fen Zheng, Bai-Ling Zhang

Article Number: 1200 Published online on: 23 August 2021
Article Open Access

Leonurine protects against ulcerative colitis by alleviating inflammation and modulating intestinal microflora in mouse models

Suna Zheng, Tianchi Zhuang, Yajun Tang, Ruihan Wu, Ting Xu, Tian Leng, Yao Wang, Zheng Lin, Minghui Ji

Article Number: 1199 Published online on: 23 August 2021
Article

Prospective evaluation of remifentanil‑propofol mixture for total intravenous anesthesia: A randomized controlled study

Mefkur Bakan, Tarik Umutoglu, Ufuk Topuz, Emine Yilmaz Guler, Harun Uysal, Erdogan Ozturk

Article Number: 1198 Published online on: 23 August 2021
Article Open Access

Astragaloside IV prevents endothelial dysfunction by improving oxidative stress in streptozotocin‑induced diabetic mouse aortas

Yang Zhang, Xiao-Dong Mao, Ai-Li Cao, Shuang Chu, Zhi-Jun Li, Yun-Man Wang, Wen Peng, Li Wang, Hao Wang

Article Number: 1197 Published online on: 20 August 2021
Article Open Access
Article Open Access

AREL1 E3 ubiquitin ligase inhibits TNF‑induced necroptosis via the ubiquitination of MTX2

Yongsam Jo, Byeongmo Kim, Deug Y. Shin

Article Number: 1195 Published online on: 20 August 2021
Retraction Open Access

[Retracted] MicroRNA‑22 inhibits cell growth and metastasis in breast cancer via targeting of SIRT1

Quanqing Zou, Qianli Tang, Yinhua Pan, Xuedi Wang, Xiaofeng Dong, Zhongxiao Liang, Dong Huang

Article Number: 1194 Published online on: 19 August 2021
Journal Cover

November-2021
Volume 22 Issue 5

Print ISSN: 1792-0981
Online ISSN: 1792-1015

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